544686-86-4

Upstream product

• 544686-85-3 2-O-(4-methoxybenzyl)-1-O-(tert-butyldiphenylsilyl)-sn-glycerol 
• 108549-21-9 benzyl-N,N,N',N'-tetraisopropylphosphorodiamidite 
• 544686-87-5 (S)-(-)-1-allyl-3-tert-butyldiphenylsilyl-sn-glycerol 
• 544686-84-2 3-O-allyl-2-O-(4-methoxybenzyl)-1-O-(tert-butyldiphenylsilyl)-sn-glycerol 

Downstream Products

• 849240-70-6 benzyl [(2S)-1,2-di-benzyloxy-propan-3-yl] [(2R)-1-hydroxy-2-(4-methoxybenzyloxy)propan-3-yl] phosphate 
• 849240-69-3 benzyl [(2S)-1,2-di-benzyloxy-propan-3-yl] [(2R)-1-tert-butyldiphenylsilyloxy-2-(4-methoxybenzyloxy)propan-3-yl] phosphate 

Relevant academic research and scientific papers

Synthesis of structural variants of Staphylococcus aureus lipoteichoic acid (LTA)

Based on 1,2-O-isopropylidene-sn-glycerol, which is readily available from d-mannitol, five chiral building blocks for the construction of structural variants of Staphylococcus aureus LTA designed and synthesized. Ligation of these building blocks led readily to the target molecules 1 and 2. They demonstrated that the d-alanine residues at the glycerophosphate backbone are decisive for the activation of the immune system.