54470-44-9Relevant articles and documents
Electro-Oxidative C-N Bond Formation through Azolation of Indole Derivatives: An Access to 3-Substituent-2-(Azol-1-yl)indoles
Zhou, Naifu,Zhao, Junhao,Sun, Chengbo,Lai, Yuqin,Ruan, Zhixiong,Feng, Pengju
, p. 16059 - 16067 (2021/10/01)
A practical protocol to synthesize 3-substituent-2-(azol-1-yl)indole derivatives has been developed via an electrochemical oxidative cross coupling process under mild conditions. This electro-oxidative C-N bond formation strategy tolerates a range of functional groups and is amenable to gram scale synthesis. Moreover, this method was applied to the late-stage functionalization of bioactive molecules.
Copper-Catalyzed Tandem O-Vinylation of Arylhydroxylamines/[3,3]-Rearrangement/Cyclization: Synthesis of Highly Substituted Indoles and Benzoindoles
Yuan, Hairui,Guo, Lirong,Liu, Fengting,Miao, Zechen,Feng, Lei,Gao, Hongyin
, p. 3906 - 3912 (2019/04/25)
Herein, we developed a copper-catalyzed O-vinylation of arylhydroxylamine using vinyliodonium salts as vinylation reagents to generate a transient O-vinyl-N-arylhydroxylamine that rapidly undergoes a [3,3]-sigmatropic rearrangement and subsequent cyclizat
Palladium Catalyzed C?C and C?N Bond Formation via ortho C?H Activation and Decarboxylative Strategy: A Practical Approach towards N-Acylated Indoles
Kumar, Saurabh,Singh, Rahul,Singh, Krishna Nand
supporting information, p. 422 - 426 (2017/11/27)
A concerted palladium catalyzed C?H activation and decarboxylative strategy has been explored for the efficient synthesis of N-acylated indoles. The process allows a facile step- and atom-economic assembly of 3-arylated indole ring from inexpensive and readily available anilides and cinnamic acids as reacting partners. (Figure presented.).
