5452-60-8

Usage

Uses

Used in Organic Synthesis:
(3R,4S)-3,4-diphenylcyclopentanone is used as a building block for the synthesis of various organic compounds due to its unique structure and reactivity.
Used in Medicinal Chemistry:
(3R,4S)-3,4-diphenylcyclopentanone is used as a key intermediate in the development of pharmaceuticals, contributing to the creation of bioactive molecules with potential therapeutic applications.
Used in Materials Science:
(3R,4S)-3,4-diphenylcyclopentanone has potential applications in the field of materials science, where its unique properties can be utilized to develop new materials with specific characteristics.
Used as a Chiral Auxiliary in Asymmetric Synthesis Reactions:
(3R,4S)-3,4-diphenylcyclopentanone is used as a chiral auxiliary to facilitate asymmetric synthesis reactions, enabling the selective formation of enantiomerically pure compounds, which is crucial in the production of pharmaceuticals and other chiral molecules.

Upstream product

• 56-23-5 tetrachloromethane 
• 4192-77-2 ethyl cinnamate 
• 108974-10-3 1r.2c-diphenyl-cyclopentanol-(4c) 
• 64-19-7 acetic acid 
• 134-81-6 benzil 
• 93260-12-9 4-chloro-3,4-diphenylcyclopent-2-en-1-one 
• 7402-06-4 3,4-diphenylcyclopent-3-enone 
• 103-26-4 Methyl cinnamate 
• 61883-07-6 meso-3,4-diphenyl-adipic acid dimethyl ester 
• 71-43-2 benzene 
• 38854-88-5 5-Hydroxy-2,3-diphenyl-cyclopent-2-enon 
• 64-17-5 ethanol 
• 4970-78-9 3,4-diphenylcyclopent-2-en-1-one 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 7433-53-6 cis-1,2-diphenylcylopentane 
• 1344674-40-3 (1R,2S)-4-(4-iodobenzyl)-1,2-diphenyl-1,2,3,4-tetrahydrocyclopenta[b]indole 
• 1344674-62-9 2-((cis)-3,4-diphenylcyclopentylidene)-1-(4-iodobenzyl)-1-phenylhydrazine 
• 24815-02-9 3ref,4cis-Dicyclohexyl-cyclopentanon 
• 24815-00-7 3ref,4cis-Dicyclohexyl-cyclopentan-cis-ol 
• 24814-94-6 3ref,4cis-Diphenyl-cyclopentan-cis-ol 
• 109470-03-3 (+/-)-cis-1.2-diphenyl-cyclopentanone-⁽⁴⁾-oxime 

Relevant academic research and scientific papers

Unexpected metal-free transformation of gem-dibromomethylenes to ketones under acetylation conditions

Novel conditions for the transformation of gem-dibromomethylenes to ketones are described. gem-Dibromo compounds were treated with acetic anhydride and triethylamine in dichloromethane/water at room temperature under an air atmosphere to give the corresponding ketones in moderate yields. A radical mechanism is proposed based on experimental results.

The catalytic asymmetric Fischer indolization

The first catalytic asymmetric Fischer indolization is reported. In the presence of a 5 mol % loading of a novel spirocyclic chiral phosphoric acid, 4-substituted cyclohexanone-derived phenylhydrazones undergo a highly enantioselective indolization. Efficient catalyst turnover was achieved by the addition of a weakly acidic cation exchange resin, which removes the generated ammonia. The reaction can be conducted under mild conditions and gives various 3-substituted tetrahydrocarbazoles in generally high yields.

Samarium(II) iodide-induced tandem reductive coupling-Dieckmann condensation reaction: One-step synthesis of bicyclic oxacyclopentanecarboxylate from bis-α,β-unsaturated esters

The tandem cyclization of bis-α,β-unsaturated esters with SmI2-Sm-THF in the presence of catalytic amount of methanol was found to stereoselectively provide bicyclo[4.3.0]nonan-8-ones and bicyclo[3.3.0]octan-3-ones.

Stereoselectivity and mechanism in the electrohydrodimerisation of esters of cinnamic acid

Rate constants (kobs) and reaction orders have been determined for the cathodic reduction in DMF solution of 11 cinnamiic acid esters including some derived from chiral alcohols and a dicinnamate derived from trans-cyclohexane-1,2-diol.The cinn