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N-(2-hydroxyphenyl)benzenesulfonamide, also known as saccharin, is an artificial sweetener with a chemical formula of C7H7NO3S. It is a white, odorless, crystalline powder that is approximately 300 times sweeter than sucrose. Saccharin is widely used in the food and beverage industry as a low-calorie sweetener, particularly in diet products, and is also found in toothpaste and mouthwashes due to its non-cariogenic properties. It has been a subject of controversy regarding its safety, but current regulations allow its use with certain restrictions and labeling requirements.

5465-16-7

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5465-16-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5465-16-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,6 and 5 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5465-16:
(6*5)+(5*4)+(4*6)+(3*5)+(2*1)+(1*6)=97
97 % 10 = 7
So 5465-16-7 is a valid CAS Registry Number.

5465-16-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(2-hydroxyphenyl)benzenesulfonamide

1.2 Other means of identification

Product number -
Other names 2-Benzolsulfamino-phenol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5465-16-7 SDS

5465-16-7Relevant academic research and scientific papers

Facile preparation and chemical transformations of spirocyclopropane-annelated heterocycles

De Meijere, Armin,Kuchuk, Ilya D.,Sokolov, Viktor V.,Labahn, Thomas,Rauch, Karsten,Es-Sayed, Mazen,Kraemer, Thomas

, p. 985 - 997 (2007/10/03)

A productive approach has been developed to spirocyclopropane-annelated 1,4-benzoxathiane 17 (85%), 1,4-benzothiazines 20-22 (56-88%) and 1,4-benzoxazines 25, 26 (55-71%), through Michael additions of binucleophilic o-hydroxythiophenol 15, o-aminothiophen

Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring

-

, (2008/06/13)

The invention relates to the field of the oxidation dyeing of keratinous fibres and in particular of human keratinous fibers, such as the hair. The invention relates more particularly to the use of certain 2-(sulphonylamino)phenols of following formula (I) as coupler in combination with oxidation dye precursors for 1the oxidation dyeing of the fibers.

1-Phenylsulfonylbenzotriazole: A novel and convenient reagent for the preparation of benzenesulfonamides and aryl benzenesulfonates

Katritzky,Zhang,Wu

, p. 205 - 216 (2007/10/02)

Readily available 1-phenylsulfonylbenzotriazole smoothly converts various aliphatic and aromatic amines and phenols into the corresponding benzenesulfonamides and benzenesulfonates in good yields.

On the mechanism of the reaction of o-benzenesulfonamide-p-benzoquinone with ammonia and amines

Gundisch,Kovar

, p. 55 - 59 (2007/10/02)

In the determination of ammonia in sera using o-benzenesulfonamido-p-benzoquinone proteins cause false positive results. These findings contradict the reaction mechanism postulated in lit., according to which a dimer is formed through an NH-bridge. As ded

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