54672-14-9

Basic information

• Product Name: 2-(DiMethylaMino)benzotrifluoride
• Synonyms: N,N-Dimethyl-2-trifluoromethylaniline
• CAS NO: 54672-14-9
• Molecular Formula: C₉H₁₀F₃N
• Molecular Weight: 189.1776096
• Mol File: 54672-14-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 188.7 °C at 760 mmHg
• Flash Point: 67.9 °C
• Appearance: /
• Density: 1.175 g/cm³
• Refractive Index: 1.46
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(DiMethylaMino)benzotrifluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(DiMethylaMino)benzotrifluoride(54672-14-9)
• EPA Substance Registry System: 2-(DiMethylaMino)benzotrifluoride(54672-14-9)

Safety Data

• Hazardous Substances Data: 54672-14-9(Hazardous Substances Data)

Usage

General Description

2-(Dimethylamino)benzotrifluoride is a chemical compound that belongs to the class of amines and is commonly used as an intermediate in the production of pharmaceuticals and agrochemicals. It has a molecular formula of C9H10F3N and a molecular weight of 189.17 g/mol. 2-(DiMethylaMino)benzotrifluoride is a colorless liquid with a boiling point of 86-87°C and a flash point of 22°C. It is known for its strong odor and is highly flammable. Additionally, it is considered to be hazardous to human health as it can cause irritation to the skin, eyes, and respiratory system. Due to its properties and potential risks, proper handling and storage guidelines should be followed when working with 2-(Dimethylamino)benzotrifluoride.

Upstream product

• 54672-13-8 4-bromo-N,N-dimethyl-2-(trifluoromethyl)-aniline 
• 1622092-08-3 2,4-dimethyl-7-(pentafluorosulfanyl)-5-(trifluoromethyl)dibenzo[b,d]thiophenium trifluoromethanesulfonate 
• 121-69-7 N,N-dimethyl-aniline 
• 64-18-6 formic acid 
• 14925-10-1 N-Methyl-2-(trifluoromethyl)aniline 
• 124-38-9 carbon dioxide 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 1092380-24-9 S-(trifluoromethyl)-4-nitrophenylphenylsulfonium triflate 
• 1092380-21-6 S-(trifluoromethyl)-4-nitrophenylphenylsulfonium tetrafluoroborate 
• 1226-46-6 thiomichlersketone 
• 54672-09-2 2-dimethylamino-5-nitrobenzotrifluoride 
• 777-37-7 4-chloro-3-(trifluoromethyl)nitrobenzene 
• 54672-12-7 N₁,N₁-dimethyl-2-(trifluoromethyl)benzene-1,4-diamine 
• 55642-42-7 bis(trifluoromethyl)tellurium 

Relevant articles and documents

The 2,4-dimethyl-7-pentafluorosulfanyl-5-(trifluoromethyl)dibenzo[b,d] thiophenium trifluoromethanesulfonate: The SF5-analog of Umemoto salt

The SF5-analog of the Umemoto salt was synthesized in just two steps by combining our recently reported SF5-biaryl synthesis, via Suzuki coupling with 4-(pentafluorosulfanyl)benzenediazonium tetrafluoroborate, with Magnier's one-pot synthesis of dibenzothiophenium salts employing CF 3SO2Na and triflic anhydride. The trifluoromethylating power of this novel onium salt toward reactive arenes was tested in a survey study on small scale.

A general catalytic methylation of amines using carbon dioxide

Putting CO2 to work: Carbon dioxide is shown to be a general and selective methylating reagent for secondary and primary, aromatic and aliphatic amines under reductive conditions. A variety of tertiary amines are obtained from CO2 and commercially available silanes in high yields with good tolerance to nitrile, olefin, ether, ester, and hydroxy groups. Copyright

A new method for the synthesis of trifluoromethylating agents-Diaryltrifluoromethylsulfonium salts

A new synthetic method has been developed to prepare diaryltrifluoromethylsulfonium salts from diaryldifluorosulfuranes by the action of Me3SiCF3/F-. This reaction is the transformation of nucleophilic trifluoro-methylating reagent into electrophilic one.