54704-39-1Relevant articles and documents
Cobalt-Catalyzed Intermolecular Markovnikov Hydroamination of Nonactivated Olefins: N2-Selective Alkylation of Benzotriazole
Yahata, Kenzo,Kaneko, Yuki,Akai, Shuji
, p. 598 - 603 (2020/02/04)
Cobalt-catalyzed Markovnikov-selective hydroamination of nonactivated olefins was developed. Hydrogen atom transfer from a catalytically generated cobalt(III)-hydride complex to the olefins proceeded regioselectively, and the nucleophilic addition of benzotriazoles occurred selectively at their N2-positions. The synthetic utility of the obtained N2-alkylated benzotriazoles as stable amine protecting groups under various reaction conditions was demonstrated, and the products were also transformed into primary amines by zinc-mediated reduction.
Synthesis of racemic lipid unit of the nucleoside antibiotic, liposidomycin-B
Kalyanakumar,Chadha,Chattopadhyay,Mamdapur
, p. 356 - 358 (2007/10/03)
The lipid part (10) of liposidomycin-B has been synthesised through functional manipulation of undecenoic acid (1) which involves chain extension via Reformatsky reaction and introduction of the methyl branching through organocuprate coupling.
REACTION OF BROMOHYDRINS WITH CHLOROTRIS(TRIPHENYLPHOSPHINE)COBALT(I)
Momose, Den-ichi,Yamada, Yasuji
, p. 2669 - 2672 (2007/10/02)
Bromohydrins were converted into ketones in high yields by the reaction with chlorotris(triphenylphosphine)cobalt(I) in the presence of amine or olefin.A probable path-way for the formation of ketones from bromohydrins was also described.