5472-61-7

Basic information

• Product Name: methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(4-nitrophenyl)propanoate
• CAS NO: 5472-61-7
• Molecular Formula: C₁₈H₁₄N₂O₆
• Molecular Weight: 354.3136
• Mol File: 5472-61-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 540.3°C at 760 mmHg
• Flash Point: 280.6°C
• Density: 1.433g/cm³
• Vapor Pressure: 9.66E-12mmHg at 25°C
• Refractive Index: 1.638
• CAS DataBase Reference: methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(4-nitrophenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(4-nitrophenyl)propanoate(5472-61-7)
• EPA Substance Registry System: methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(4-nitrophenyl)propanoate(5472-61-7)

Safety Data

• Hazardous Substances Data: 5472-61-7(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 4306-25-6 (S)-2-phthalimidopropionyl chloride 
• 4192-28-3 Phth-L-Ala-OH 
• 67-56-1 methanol 
• 56613-61-7 (R)-4-nitro-phenylalanine 
• 131175-70-7 (R)-N-phthaloyl-p-nitrophenylalanine 

Relevant articles and documents

Pd(II)-catalyzed C(sp3)-H arylation of amino acid derivatives with click-triazoles as removable directing groups

By using click-triazoles as conveniently approachable and removable directing groups, the direct palladium-catalyzed C(sp3)-H arylation of amino acid derivatives with various aryl iodides bearing different electronic properties has been achieved. Notably, the desired amino acid molecule can be obtained by the cleavage of the tethered click-triazoles after the catalytic reaction, which aims to provide a practical protocol for the accessibility of both natural and synthetic amino acids.