54722-44-0Relevant academic research and scientific papers
Solution-phase parallel synthesis of benzoxazines using a polymer-supported carbodiimide
Buckman, Brad O.,Morrissey, Michael M.,Mohan, Raju
, p. 1487 - 1488 (1998)
A diverse library of 2-aminobenzoxazines 3 has been synthesized using a two step approach. Addition of anthranilic acids to isocyanates affords ureas 2 that can be cyclized by polymer-supported EDC to give 2-aminobenzoxazines 3.
A convenient palladium-catalyzed carbonylative synthesis of 2-aminbenzoxazinones from 2-bromoanilines and isocyanates
Wu, Xiao-Feng,Sharif, Muhammad,Shoaib, Khurram,Neumann, Helfried,Pews-Davtyan, Anahit,Langer, Peter,Beller, Matthias
supporting information, p. 6230 - 6233 (2013/07/05)
Mon ami(ne)! A general and convenient methodology for 2-aminobenzoxazinone synthesis has been developed (see scheme). Readily available 2-bromoanilines and isocyanates were used as substrates and various products have been prepared in good yields. Notably, [Mo(CO)6] as a solid CO source was applied instead of gas. Copyright
Tetrabutylammonium fluoride promoted intramolecular nucleophilic attack of an ester group on a carbodiimide: Preparation of 1,3-oxazolin-5-ones and 3,1-benzoxazin-4-ones
Molina,Aller,Ecija,Lorenzo
, p. 690 - 692 (2007/10/03)
Functionalized carbodiimides bearing an ester group either at the α or β position undergo cyclization in the presence of tetrabutylammonium fluoride (TBAF) under mild conditions to give 1,3-oxazolin-5-ones or 3,1-benzoxazin-4-ones in synthetically useful yields.
Convenient Preparation of N-substituted 2-Amino-4H-3,1-benzoxazin-4-ones and 3-Substituted 2,4(1H,3H)-Quinazolinediones
Papadopoulos, E. P.,Torres, C. D.
, p. 269 - 272 (2007/10/02)
Room temperature of 2-(3-arylureido)benzoic acids (1) and methyl2-(3-alkyl-, or 3-arylureido)-benzoates (2) with concentrated sulfuric acid leads to N-substituted 2-amino-4H-3,1-benzoxazin-4-ones (3) in generally very good yields.The isomeric 3-substitute
