54757-44-7

Basic information

• Product Name: [5-(4-Methoxy-2,3,6-trimethylphenyl)-3-methyl-2,4-pentadien-1-yl]triphenylphosphonium bromide
• Synonyms: [5-(4-Methoxy-2,3,6-trimethylphenyl)-3-methyl-2,4-pentadien-1-yl]triphenylphosphonium bromide;(5-(4-Methoxy-2,3,6-trimethylphenyl)-3-methylpenta-2,4-dien-1-yl)triphenylphosphonium bromide
• CAS NO: 54757-44-7
• Molecular Formula: C34H36OP.Br
• Molecular Weight: 572
• Mol File: 54757-44-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: [5-(4-Methoxy-2,3,6-trimethylphenyl)-3-methyl-2,4-pentadien-1-yl]triphenylphosphonium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: [5-(4-Methoxy-2,3,6-trimethylphenyl)-3-methyl-2,4-pentadien-1-yl]triphenylphosphonium bromide(54757-44-7)
• EPA Substance Registry System: [5-(4-Methoxy-2,3,6-trimethylphenyl)-3-methyl-2,4-pentadien-1-yl]triphenylphosphonium bromide(54757-44-7)

Safety Data

• Hazardous Substances Data: 54757-44-7(Hazardous Substances Data)

Usage

Uses

(5-(4-Methoxy-2,3,6-trimethylphenyl)-3-methylpenta-2,4-dien-1-yl)triphenylphosphonium bromide is a useful research chemical compound.

Upstream product

• 54757-47-0 4-(4'-methoxy-2',3',6'-trimethylphenyl)-but-3-ene-2-one 
• 6399-81-1 triphenylphosphine hydrobromide 
• 54757-48-1 5-(4-methoxy-2,3,6 trimethylphenyl)-3-methylpenta-1,4-dien-3-ol 
• 54344-92-2 2,3,6-trimethyl-4-methoxy-benzaldehyde 
• 124743-93-7 (2Z)-5-(4-Methoxy-2,3,6-trimethylphenyl)-3-methylpent-2-en-4-in-1-ol 
• 84244-55-3 1-bromo-4-methoxy-2,3,6-trimethylbenzene 
• 6153-05-5 (Z)-3-methylpent-2-en-4-ynol 
• 20469-61-8 2,3,5-trimethylanisole 

Downstream Products

• 74479-40-6 butyl {(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethyl)phenyl-3,7-dimethylnona-2,4,6.8}tetraenoate 

Relevant articles and documents

PROCESS FOR PREPARATION OF ACITRETIN

The present invention provides a process for preparation of {(2E,4E,6E,8E)-9-(4-methoxy-2,3,6- trimethyl)phenyl-3,7-dimethyl-nona-2,4,6,8}tetraenoate, an acitretin intermediate of formula (VI) with trans isomer ≥97%, comprising of reacting 3-formyl-crotonic acid butyl ester of formula (V), substantially free of impurities, with 5-(4-methoxy-2,3,6-trimethylphenyl)-3- methyl-penta-2,4-diene-l-triphenyl phosphonium bromide of formula (IV) and isolating resultant compound of formula (VI), treating the filtrate with iodine for isomerization of the undesired cis intermediate and finally obtaining acitretin (I), with desired trans isomer ≥97%.