54831-51-5

Upstream product

• 54947-74-9 (4R)-4-Methyloctanoic acid 
• 64-17-5 ethanol 
• 7540-51-4 (S)-3,7-dimethyl-6-octen-1-ol 
• 3285-00-5 dihydro-5-butyl-5-methyl-2-(3H)-furanone 
• 54947-74-9 rac-4-methyloctanoic acid 
• 624-21-5 1-iodo-2-methyl-hexane 
• 128342-72-3 (4S)-4-methyloctanoic acid 
• 1117-61-9 (3R)-citronellol 
• 171627-80-8 (4S)-Methyloctanal 
• 171627-78-4 (6S)-2,6-Dimethyl-2-decene 
• 67214-54-4 (R)-citronellyl tosylate 
• 105-53-3 diethyl malonate 
• 79909-21-0 ethyl γ-iodovalerate 
• 693-04-9 butyl magnesium bromide 

Downstream Products

• 17302-27-1 (-)(R)-2.5-dimethyl-nonane 

Relevant academic research and scientific papers

Concise asymmetric syntheses of (S)-ethyl 4-methyloctanoate and its acid: Aggregation pheromones of rhinoceros beetles of the genus Oryctes

A concise stereoselective approach to the asymmetric syntheses of (S)-ethyl 4-methyloctanoate and its acid, main aggregation pheromones of the genus Oryctes and an important fragrance compounds, is described. The synthesis utilizes the organocatalyzed Mac

METHOD FOR PRODUCING ETHYL 4-METHYLOCTANOATE

There is provided a method for producing ethyl 4-methyloctanoate at a lower cost, by fewer steps, and in higher yield. More specifically, there is provided a method for producing ethyl 4-methyloctanoate comprising the steps of: reacting 1-chloro-2-methylhexane through malonic ester synthesis to obtain diethyl 2-methylhexylmalonate, and subjecting the diethyl 2-methylhexylmalonate to a Krapcho reaction to obtain ethyl 4-methyloctanoate.

Efficient synthesis of (±)-4-methyloctanoic acid, aggregation pheromone of rhinoceros beetles of the genus oryctes (Coleoptera: Dynastidae, Scarabaeidae)

(±)-4-Methyloctanoic acid and its ethyl ester are aggregation pheromones of many rhinoceros beetles of the genus Oryctes and are investigated for the control of these pests by olfactory trapping. A simple, economical, and high-yield (>50%) synthesis of (±)-4-methyloctanoic acid and its ethyl ester is presented starting from n-hexanal. The key step in this sequence is an orthoester Claisen rearrangement for the elongation of the carbon chain by two.

Substrate sorption into the polymer matrix of Novozym 435 and its effect on the enantiomeric ratio determination

In the enantioselective esterification of 4-methyloctanoic acid with ethanol by immobilised Candida antarctica lipase B (Novozym 435), the enantiomeric excesses determined during the course of the reaction deviated strongly from the theoretical values, le

A New Coupling Reaction of Alkyl Iodides with Electron Deficient Alkenes Nickel Boride (cat.) - Borohydride Exchange Resin in Methanol

The radical addition reaction of alkyl iodides with α,β-unsaturated esters, nitriles, and ketones proceeds in moderate to excellent yields (50-95%) using Ni(OAc)2 (0.05-0.2 equiv) - BER (3-5 equiv) in methanol in 1-9 h at room temperature or at 65°C. Nickel boride on borohydride exchange resin (BER) is a good alternative reagent to tributyltin hydride for the coupling of alkyl iodides with the electron deficient alkenes in methanol. Compared with tributyltin hydride method, this method has an advantage of simple workup, since nickel boride - BER can be removed readily by filtration.

A new coupling reaction of alkyl iodides with α,β-unsaturated esters using Ni2B(cat.)-BER in methanol

Alkyl iodides can be coupled with α,β-unsaturated esters using Ni2B(0.05-0.2 eq)-BER(3 eq) in methanol at room temperature. Products (68-95%) are conveniently isolated, simply filtering the resin and evaporating the excess enoates and methanol.