548792-14-9Relevant academic research and scientific papers
An efficient synthesis of novel estrieno[2.3-b] and [3.4-c]pyrroles
Zhang, Xuqing,Sui, Zhihua
, p. 3071 - 3073 (2003)
An efficient protocol for the preparation of novel estrieno[2.3-b] and [3.4-c]pyrroles 1 and 2 using Pd(0)-catalyzed amination and Bischler indole synthesis is described.
Metal-Free Geminal Difunctionalization of Diazocarbonyl Compounds: A One-Pot Multicomponent Strategy for the Construction of α,β-Diamino Carbonyl Derivatives
Zhu, Dan,Yao, Yuan,Zhao, Rong,Liu, Yang,Shi, Lei
, p. 4805 - 4809 (2018/03/21)
An unprecedented three-component domino oxidative coupling of diazocompounds for the efficient synthesis of α-azido-β-amino esters with non-activated dimethylamino compounds and simple TMSN3 was achieved. The main features of this method include metal-free catalysis, satisfactory functional group tolerance, general applicability in complex molecule architectures, and excellent diastereoselectivity in the presence of chiral auxiliaries. In addition, several related control experiments have been conducted to investigate the reaction mechanism.
Metal- and Base-Free Room-Temperature Amination of Organoboronic Acids with N-Alkyl Hydroxylamines
Sun, Hong-Bao,Gong, Liang,Tian, Yu-Biao,Wu, Jin-Gui,Zhang, Xia,Liu, Jie,Fu, Zhengyan,Niu, Dawen
supporting information, p. 9456 - 9460 (2018/07/29)
We have found that readily available N-alkyl hydroxylamines are effective reagents for the amination of organoboronic acids in the presence of trichloroacetonitrile. This amination reaction proceeds rapidly at room temperature and in the absence of added metal or base, it tolerates a remarkable range of functional groups, and it can be used in the late-stage assembly of two complex units.
An improved synthesis of 3-aminoestrone
Sch?n, Uwe,Messinger, Josef,Buchholz, Monika,Reinecker, Uwe,Thole, Hubert,Prabhu, Manoj K. S.,Konda, Ashok
, p. 7111 - 7115 (2007/10/03)
An efficient Pd(0)-catalyzed protocol for the rapid and efficient preparation of 3-aminoestrone via 3-benzylaminoestrone from estrone-triflate is described. The three step synthesis proceeds with an overall yield of about 55% using X-Phos as optimal ligan
