57629-47-7

Basic information

• Product Name: Oxazole, 2-(2-butylphenyl)-4,5-dihydro-4,4-dimethyl-
• CAS NO: 57629-47-7
• Molecular Formula: C15H21NO
• Molecular Weight: 231.338
• Mol File: 57629-47-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Oxazole, 2-(2-butylphenyl)-4,5-dihydro-4,4-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 2-(2-butylphenyl)-4,5-dihydro-4,4-dimethyl-(57629-47-7)
• EPA Substance Registry System: Oxazole, 2-(2-butylphenyl)-4,5-dihydro-4,4-dimethyl-(57629-47-7)

Safety Data

• Hazardous Substances Data: 57629-47-7(Hazardous Substances Data)

Upstream product

• 98191-99-2 2-(2-chlorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole 
• 80762-49-8 2-(m-chlorophenyl)-4,4-dimethyl-4,5-dihydrooxazole 
• 535-80-8 3-chlorobenzoate 
• 701923-86-6 3-Chloro-N-(2-hydroxy-1,1-dimethyl-ethyl)-benzamide 
• 109-72-8 n-butyllithium 
• 693-03-8 n-butyl magnesium bromide 
• 57598-33-1 2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline 
• 89393-50-0 benzyne 
• 618-46-2 m-Chlorobenzoyl chloride 
• 19312-06-2 4,5-dihydro-4,4-dimethyl-2-phenoxazole 
• 542-69-8 1-iodo-butane 

Downstream Products

• 115890-86-3 2-(2-n-butyl-6-methylphenyl)-4,4-dimethyl-2-oxazoline 
• 54887-24-0 2-butylbenzoyl chloride 
• 177903-44-5 (2-Butyl-benzoyl)-phosphonic acid dimethyl ester 
• 1595-11-5 2-butyltoluene 
• 112562-04-6 2-(2-Butyl-phenyl)-thiazolidine-3-carbothioic acid methylamide 
• 59059-42-6 2-butylbenzaldehyde 
• 100256-40-4 2-(n-Butyl)-benzoesaeuremethylester 
• 87306-66-9 2-(2-Butyl-benzylamino)-2-methyl-propan-1-ol 
• 54887-23-9 2-butylbenzoic acid 
• 115890-88-5 2-(2,6-dibutylphenyl)-4,5-dihydro-4,4-dimethyl-1,3-oxazole 

Relevant articles and documents

Manganese-catalyzed substitution of activated aryl halides (X = Cl, Br and F) and aryl ethers by organomagnesium reagents

In the presence of manganese chloride (10%), Grignard reagents readily react in THF with aryl bromides, chlorides and even fluorides, as well as aryl methyl ethers bearing in the ortho- or para-position an electron withdrawing activating group (CN, CH=NR, oxazoline). Aryl and N- or S- alkylmagnesium halides have been used successfully. The reaction is performed under mild conditions (0 °C to room temperature, 30 minutes to 24 hours) and leads to cross-coupling products in good yields.

Palladium-mediated ortho-alkylation of 2-aryloxazolines

The regioselective ortho-alkylation of 2-aryloxazolines through the reaction of their cyclopalladated complexes with 1-iodoalkanes is described.Depending upon the experimental conditions, either 2- or 2,6-substituted derivatives can be selectively prepare

THE SYNTHESIS OF 1,2,3-TRISUBSTITUTED BENZENES. FURTHER COMMENTS ON BENZYNES DERIVED FROM ARYL OXAZOLINES

Further investigation of organolithium addition to the 2,3-benzyne of aryl oxazolines reveals that addition takes place to give the 3-lithio (kinetic) and/or 2-lithio (thermodynamic) products depending on the nature of the organolithium reagent.