Welcome to LookChem.com Sign In|Join Free

CAS

  • or

5499-67-2

Post Buying Request

5499-67-2 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

5499-67-2 Usage

Description

5-CHLORO-1,3-DIPHENYL-1H-PYRAZOLE-4-CARBALDEHYDE is a chemical compound with the molecular formula C19H13ClN2O. It is a pyrazole derivative that features a chloro group, two phenyl rings, and an aldehyde functional group. This unique structure endows it with potential applications in various fields, particularly in the pharmaceutical industry for the development of new drugs. Additionally, it may serve as a valuable starting material in organic synthesis and chemical research.

Uses

Used in Pharmaceutical Industry:
5-CHLORO-1,3-DIPHENYL-1H-PYRAZOLE-4-CARBALDEHYDE is used as a key intermediate in the synthesis of new drugs, leveraging its distinctive chemical structure to create novel therapeutic agents.
Used in Organic Synthesis:
In the realm of organic synthesis, 5-CHLORO-1,3-DIPHENYL-1H-PYRAZOLE-4-CARBALDEHYDE is utilized as a starting material for the creation of a variety of other compounds, contributing to the development of new chemical entities.
Used in Chemical Research:
5-CHLORO-1,3-DIPHENYL-1H-PYRAZOLE-4-CARBALDEHYDE also serves as a valuable component in chemical research, where its properties and reactivity are studied to further scientific understanding and innovation.

Check Digit Verification of cas no

The CAS Registry Mumber 5499-67-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,9 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5499-67:
(6*5)+(5*4)+(4*9)+(3*9)+(2*6)+(1*7)=132
132 % 10 = 2
So 5499-67-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H11ClN2O/c17-16-14(11-20)15(12-7-3-1-4-8-12)18-19(16)13-9-5-2-6-10-13/h1-11H

5499-67-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-chloro-1,3-diphenylpyrazole-4-carbaldehyde

1.2 Other means of identification

Product number -
Other names 5-chloro-1,3-diphenyl-1H-pyrazole-4-carboxaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5499-67-2 SDS

5499-67-2Relevant articles and documents

A novel synthetic method of organoselenum compounds

-

Paragraph 0122-0126; 0127-0132; 0157-0162, (2021/09/07)

The present application can synthesize a selenopyrano pyrazolone derivative, one of an organic selenium compound, in a simple and excellent yield. Provided is a synthesis method of an organic selenium compound which is eco-friendly at low temperature and

New hydrazone derivatives of pyrazole-4-carboxaldehydes exhibited anti-inflammatory properties

Chen, Qiuyan,Deng, Xianqing,He, Shihui,Li, Sifan,Liang, Yuqiu,Liu, Bing,Song, Mingxia,Yu, Shengwang

, p. 501 - 510 (2020/04/17)

Background: Several series of hydrazone derivatives of pyrazole-4-carboxaldehydes (4-11) were designed and synthesized to screen their inflammatory activity. Methods: The products were characterized by1H NMR,13C NMR and HRMS. In vitro LPS-induced TNF-α model and in vivo xylene-induced ear-edema model were used to evaluate their anti-inflammatory activity. Results and Conclusion: Bioassays indicated that most of the compounds markedly inhibited the expression of TNF-α at the concentration of 10 μg/mL. Compounds 7b and 11c, two of the most potent compounds, exhibited TNF-α inhibitory ability in a dose-dependent manner with IC50 values of 5.56 and 3.69 μM, respectively. In vivo, intraperitoneal administration with 7b and 11c markedly inhibited the ear edema at the doses of 20 and 50 mg/kg. Compound 11c, inhibited edema by 49.59 % at the dose of 20 mg/kg, was comparable to the reference drug dexamethasone at the same dose (with an inhibition of 50.49 %). To understand the binding pattern, molecular docking of representa-tive 7b and 11c was performed, which demonstrated that both compounds have a forceful binding with the TNF-α, and that the phenyl and hydrazide moieties of them play a significant role in binding with the target site.

Microwave-accelerated and Catalyst-free Synthesis of Novel tris-(Pyrazolyl)methanes

Beyrati, Maryam,Hasaninejad, Alireza

, p. 393 - 400 (2016/09/14)

-

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 5499-67-2