55000-14-1

Basic information

• Product Name: 2-[(2-methylprop-2-en-1-yl)oxy]aniline
• Synonyms: 2-[(2-methylprop-2-en-1-yl)oxy]aniline;UKRORGSYN-BB BBV-183418;2-[(2-methylprop-2-en-1-yl)oxy]aniline(SALTDATA: HCl);2-(2-methylprop-2-enoxy)aniline
• CAS NO: 55000-14-1
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.22
• Mol File: 55000-14-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: 80-80.5 °C
• Boiling Point: 274.1°C at 760 mmHg
• Flash Point: 122.3°C
• Appearance: /
• Density: 1.019g/cm³
• Vapor Pressure: 0.00551mmHg at 25°C
• Refractive Index: 1.545
• PKA: 4.33±0.10(Predicted)
• CAS DataBase Reference: 2-[(2-methylprop-2-en-1-yl)oxy]aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2-methylprop-2-en-1-yl)oxy]aniline(55000-14-1)
• EPA Substance Registry System: 2-[(2-methylprop-2-en-1-yl)oxy]aniline(55000-14-1)

Safety Data

• Hazardous Substances Data: 55000-14-1(Hazardous Substances Data)

Usage

Physical state

Colorless to pale yellow liquid

Odor

Characteristic amine odor

Solubility

Insoluble in water, soluble in organic solvents

Usage

Production of dyes, pharmaceuticals, and other organic chemicals

Health hazards

Skin and eye irritant, potential carcinogen

Safety measures

Requires careful handling and proper safety precautions

InChI:InChI=1/C10H13NO/c1-8(2)7-12-10-6-4-3-5-9(10)11/h3-6H,1,7,11H2,2H3

Upstream product

• 186663-74-1 tert-butyl (2-hydroxyphenyl)carbamate 
• 95-55-6 2-amino-phenol 
• 1458-98-6 2-methyl-3-bromo-1-propene 
• 88-75-5 2-hydroxynitrobenzene 
• 614-80-2 2-(acetylamino)phenol 
• 13414-54-5 2-[(2-methyl-2-propenyl)oxy]-1-nitrobenzene 
• 88924-86-1 N-(2-((2-methylallyl)oxy)phenyl)acetamide 

Downstream Products

• 56182-25-3 1-(2-((2-methylallyl)oxy)phenyl)-2-(tetrafluoro-λ⁵-boraneyl)diazene 

Relevant articles and documents

SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted, saturated and unsaturated N-heterocyclic carboxamides and related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., cancer, lysosomal storage disorder, neurodegenerative disorder, inflammatory disorder, in a patient.

Chiral N,N Ligands Enabling Palladium-Catalyzed Enantioselective Intramolecular Heck–Matsuda Carbonylation Reactions by Sequential Migratory and CO Insertions

Unprecedented enantioselective intramolecular Heck carbonylation reactions of arenediazonium salts were enabled by a chiral N,N ligand. This reaction constitutes the first enantioselective Heck carbonylation that proceeds through migratory insertion followed by CO insertion. The enantioenriched functionalized dihydrobenzofurans were obtained in good to high yields and enantiomeric ratios of up to 98:2 under mild and operationally simple reaction conditions.

Cyclizing radical carboiodination, carbotelluration, and carboaminoxylation of aryl amines

Radical carboiodination of various aryl amines is reported. Aryl diazonium salts, generated in situ from the corresponding aryl amines, are reacted with Bu4NI to provide the corresponding aryl radicals which undergo 5-exo or 6-exo cyclization. Iodine abstraction eventually affords the carboiodinated products in good to excellent yields. If TEMPO is added, the cascade provides the cyclized carboaminoxylation products. Running the reaction in the presence of PhTeTePh affords the phenyltellurated cyclized products.