55041-14-0Relevant articles and documents
Expeditious and Highly Efficient One-Pot Synthesis of Functionalized Imidazoles Catalyzed by Sulfated Polyborate
Indalkar, Krishna,Malge, Sanjay S.,Mali, Anil S.,Chaturbhuj, Ganesh U.
, p. 387 - 396 (2021/07/26)
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One-Pot, Two-Step Metal and Acid-Free Synthesis of Trisubstituted Imidazole Derivatives via Oxidation of Internal Alkynes Using an Iodine/DMSO System
Naidoo, Shivani,Jeena, Vineet
, p. 1107 - 1113 (2019/01/04)
A one-pot, two-step, simple, efficient and eco-friendly oxidation of internal alkynes as a key step towards the synthesis of 2,4,5-trisubstituted imidazoles, using an inexpensive I2/DMSO system, has been reported. This metal and acid-free synthesis proceeded smoothly to furnish a variety of synthetically useful trisubstituted imidazoles in moderate to excellent yields. In an effort to demonstrate the potential future applications of this system, a double oxidation study was undertaken and the desired trisubstituted imidazoles obtained in good to moderate yields.
Copper-catalyzed aerobic benzylic sp3 C-H oxidation mediated synthesis of 2,4,5-trisubstituted imidazoles via a domino multi-component reaction
Jayram, Janeeka,Jeena, Vineet
supporting information, p. 5841 - 5845 (2017/12/26)
An efficient and practical aerobic benzylic sp3 C-H oxidation as a key step towards the domino multi-component synthesis of 2,4,5-trisubstituted imidazoles has been reported. This green methodology employs an inexpensive catalytic copper/oxygen system and proceeds under mild reaction conditions. A variety of substituted imidazoles are prepared in moderate to excellent yields from α-methylene ketones using this innovative methodology.