55111-70-1

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 1457-46-1 3-phenylrhodanine 
• 36937-45-8 5-(4-Methoxyphenylmethylene)-2-morpholino-2-thiazolin-4-one 
• 1010-53-3 3-phenyl-2,4-thiazolidinedione 

Downstream Products

• 102594-44-5 5-(4-methoxy-benzhydryl)-3-phenyl-2-thioxo-thiazolidin-4-one 
• 93515-30-1 3-(4-methoxyphenyl)-2-sulfanylpropenoic acid 
• 103-72-0 phenyl isothiocyanate 
• 1397692-20-4 (5S,6S,10S)-6-(4-methoxyphenyl)-3,10-diphenyl-2-thioxo-1-thia-3-azaspiro[4.5]decane-4,8-dione 
• 1426097-56-4 ((5S,6R,10S)-10-(4-methoxyphenyl)-4-oxo-3-phenyl-2-thioxo-1-thia-3-azaspiro[4.5]dec-7-en-6-yl)acetaldehyde 
• 473713-31-4 7-(4-methoxy-phenyl)-4-phenyl-2,6-dithia-4-aza-bicyclo[3.2.0]hept-1⁽⁵⁾-ene-3-thione 
• 181132-80-9 7-[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-1,3,9-triphenyl-4,6-dithia-1,2,9-triaza-spiro[4.4]non-2-en-8-one 
• 181132-86-5 3-Acetyl-7-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-1,9-diphenyl-4,6-dithia-1,2,9-triaza-spiro[4.4]non-2-en-8-one 

Relevant academic research and scientific papers

Synthesis of 5-substituted 2-ylidene-1,3-thiazolidin-4-one derivatives and evaluation of their anticancer and antioxidant activities

[Figure not available: see fulltext.] Novel 5-(aroyl)methyl- and 5-(aroyl)methylen-2-ylidene-1,3-thiazolidin-4-ones have been prepared in high yields using ketene N,S-acetal salts, obtained from phenyl isothiocyanate and propanedinitrile or ethyl cyanoacetate. Several of the newly synthesized 1,3-thiazolidin-4-one derivatives demonstrate high antioxidant and anticancer activities.

Reactions of N,N-Disubstituted 5-arylmethylidene-2-aminothiazol-4(5H)-ones with CH acids

N,N-Disubstituted 5-arylmethylidene-2-aminothiazol-4(5H)-ones reacted with diethyl malonate, ethyl benzoylacetate, acetylacetone, or cyclopentadiene in refluxing toluene and in presence of powdered sodium to give the respective 5-arylmethylidene-2′-amino-

A convenient synthesis of 3,5-diarylthieto[2,3-d]thiazole-2-thiones, and expansion of their thiete ring with carbon disulphide

3-Aryl-5-arylidenerhodanines 3a-f react with 0,0-diethyl hydrogen phosphorodithioate 4 to yield 3,5-diarylthieto[2,3-d]thiazole-2-thiones 6a-f in a one-pot procedure. The compounds 6a-f undergo expansion of their thiete ring by the reaction with carbon disulphide, catalysed by lithium iodide, to afford the corresponding 3,7-diarylthiazolo[4,5-d]-1,3-dithiin-2,5-dithiones 7a-f in high yields under mild conditions.

Synthesis and insecticidal activity of 5-amino-7-aryl-6-cyano-3-substituted-thiazolo-2,3,4,7-tetrahydropyridine-2-thione and 7-aryl-6-cyano-3-substituted-2-thioxo-thiazolo-2,3,4,5,6,7-hexahydropyridin-5-one

5-Amino-7-aryl-6-cyano-3-substituted-thiazolo-2,3,4,7-tetrahydropyridine-2-thione 3 and 7-aryl-6-cyano-3-substituted-2-thioxo-thiazolo-2,3,4,5,6,7-hexahydropyridin-5-one 4 have been prepared by Michael addition between α,β-unsaturated ketone