4-Thiazolidinone, 5-[(4-methoxyphenyl)methylene]-3-phenyl-2-thioxo-

Base Information

Chemical Name:4-Thiazolidinone, 5-[(4-methoxyphenyl)methylene]-3-phenyl-2-thioxo-
CAS No.:55111-70-1
Molecular Formula:C17H13NO2S2
Molecular Weight:327.428
Hs Code.:
DSSTox Substance ID:DTXSID60389181

Synonyms:55111-70-1;4-Thiazolidinone, 5-[(4-methoxyphenyl)methylene]-3-phenyl-2-thioxo-;DTXSID60389181

Suppliers and Price of 4-Thiazolidinone, 5-[(4-methoxyphenyl)methylene]-3-phenyl-2-thioxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-Thiazolidinone, 5-[(4-methoxyphenyl)methylene]-3-phenyl-2-thioxo-

Chemical Property:

PSA：86.93000
LogP:4.16600
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:327.03877100
Heavy Atom Count:22
Complexity:463

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)C3=CC=CC=C3

Technology Process of 4-Thiazolidinone, 5-[(4-methoxyphenyl)methylene]-3-phenyl-2-thioxo-

There total 6 articles about 4-Thiazolidinone, 5-[(4-methoxyphenyl)methylene]-3-phenyl-2-thioxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1457-46-1
3-phenylrhodanine

: 123-11-5
4-methoxy-benzaldehyde

: 55111-70-1
(5E,5Z)-5-(4-methoxybenzylidene)-3-phenyl-2-thioxo-1,3-thiazolidin-4-one

Guidance literature:: With sodium acetate; In acetic acid; Heating;

Reference yield: 74.0%

: 36937-45-8
5-(4-Methoxyphenylmethylene)-2-morpholino-2-thiazolin-4-one

: 1457-46-1
3-phenylrhodanine

: 55111-70-1
(5E,5Z)-5-(4-methoxybenzylidene)-3-phenyl-2-thioxo-1,3-thiazolidin-4-one

Guidance literature:: 3-phenylrhodanine; With sodium; In toluene; for 1h; Heating;

5-(4-Methoxyphenylmethylene)-2-morpholino-2-thiazolin-4-one; In toluene; for 4h; Heating;
DOI:10.1007/s007060200092

Reference yield:

: 1010-53-3
3-phenyl-2,4-thiazolidinedione

: 55111-70-1
(5E,5Z)-5-(4-methoxybenzylidene)-3-phenyl-2-thioxo-1,3-thiazolidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: phenyl isothiocyanate; potassium hydroxide / ethanol / 0.5 h / 0 °C

1.2: 0.5 h / 0 °C

1.3: 0.08 h / Reflux

2.1: acetic acid; sodium acetate / 0.5 h / Reflux

With sodium acetate; phenyl isothiocyanate; acetic acid; potassium hydroxide; In ethanol;
DOI:10.1007/s10593-019-02568-5