55153-25-8Relevant academic research and scientific papers
Palladium-Catalyzed Chemo- and Enantioselective C?O Bond Cleavage of α-Acyloxy Ketones by Hydrogenolysis
Chen, Jianzhong,Zhang, Zhenfeng,Liu, Delong,Zhang, Wanbin
supporting information, p. 8444 - 8447 (2016/07/19)
A chemoselective C?O bond cleavage of the ester alkyl side-chain of α-acyloxy ketones was realized for the first time by a highly efficient palladium-catalyzed hydrogenolysis (S/C=6000, the highest catalytic efficiency by far). Furthermore, a kinetic resolution of α-acyloxy ketones was first developed by enantioselective hydrogenolysis with good yields and up to 99 % ee.
Palladium-catalyzed asymmetric hydrogenation of α-acyloxy-1- arylethanones
Chen, Jianzhong,Liu, Delong,Butt, Nicholas,Li, Chao,Fan, Dongyang,Liu, Yangang,Zhang, Wanbin
supporting information, p. 11632 - 11636 (2013/11/06)
First hand: The first example of a palladium-catalyzed asymmetric hydrogenation of α-acyloxy ketones (1) was accomplished to give the hydrogenated products 2 with by far the highest catalytic efficiency in up to quantitative conversions and excellent enantioselectivities. The hydrogenated products could serve as important intermediates for the preparation of many drug candidates. TFE=2,2,2-trifluoroethanol. Copyright
Organic Reactions in Ionic Liquids: Ionic Liquid-Accelerated Nucleophilic Substitution Reaction of α-Tosyloxyketones with Potassium Salts of Aromatic Acids
Liu, Zhi,Chen, Zhen-Chu,Zheng, Qin-Guo
, p. 33 - 36 (2007/10/03)
The room temperature ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]) is used as a 'green' recyclable alternative to classical molecular solvents for the nucleophilic substitution reaction of α-tosyloxy ketones with pota
Synthesis of phenacyl esters by using PTC and dibenzo-[18)-crown-6
Jugdale,Patil,Salunkhe
, p. 1747 - 1752 (2007/10/03)
In view of the importance of phenacyl esters as a protecting groups, a simple and efficient method is now reported here for synthesis of phenacyl esters in quantitative yield and high purity under mild reaction condition by using phase transfer catalyst a
Separation of Polar and Steric Effects in Reactions of ortho-Substituted Benzoate Ions with para-Substituted Phenacyl Bromides
Srinivasan, C.,Shunmugasundaram, A.,Roja, M.,Arumugam, N.
, p. 555 - 557 (2007/10/02)
The second order rate constants for SN2 reactions of several ortho-substituted benzoate ions with several para-substituted phenacyl bromides have been measured in 90percent acetone - 10percent water (v/v) mixture at 35 deg C.Satisfactory correl
Influence of ortho-Substituents in Anionic Surfactant Catalyzed Reaction of Benzoate Ions with Phenacyl Bromide
Behera, G. B.,Mishra, S. S.,Pujhari, M.
, p. 558 - 560 (2007/10/02)
The reaction of ortho-substituted benzoate ions and phenacyl bromide in the presence of anionic surfactant, sodium dodecyl sulphate (NaLS) has been studied in acetone-water (68:32, v/v) at 35 deg C.A plot of rate constants versus surfactant concentrations
