5520-22-9

Usage

Uses

Used in Coordination Chemistry:
2-(4-phenylbutyl)pyridine is utilized as a ligand for the formation of coordination compounds. Its unique structure allows it to bind with metal ions, facilitating the creation of complexes with specific properties and applications.
Used in Catalysis:
In the field of catalysis, 2-(4-phenylbutyl)pyridine serves as a catalyst or a catalyst precursor. Its ability to form complexes with metal ions enhances the reactivity and selectivity of catalytic processes, making it a valuable component in various chemical reactions.
Used in Organic Synthesis:
2-(4-phenylbutyl)pyridine is employed as a building block or intermediate in organic synthesis. Its structural features enable the synthesis of a range of organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals.
Used in Medicinal Chemistry:
2-(4-phenylbutyl)pyridine is explored for its potential applications in medicinal chemistry. Its unique structure and properties may contribute to the development of new drugs and therapeutic agents, particularly in the areas of central nervous system disorders, cardiovascular diseases, and oncology.
Used in Fragrance Industry:
Leveraging its aromatic and sweet odor, 2-(4-phenylbutyl)pyridine is used as a fragrance ingredient in the perfumery and cosmetics industry. It adds depth and complexity to fragrance compositions, enhancing the sensory experience of various products.
Used in Flavor Industry:
2-(4-phenylbutyl)pyridine also finds application in the flavor industry, where it is employed to impart specific taste profiles to food and beverages. Its unique aroma and flavor characteristics contribute to the development of innovative and appealing taste experiences.

InChI:InChI=1/C15H17N/c1-2-8-14(9-3-1)10-4-5-11-15-12-6-7-13-16-15/h1-3,6-9,12-13H,4-5,10-11H2

Upstream product

• 109-06-8 α-picoline 
• 104-52-9 phenylpropyl chloride 
• 15295-69-9 hept-6-ynenitrile 
• 74-86-2 acetylene 
• 100-69-6 2-vinylpyridine 
• 34420-17-2 (2-phenylethyl)boronic acid 
• 2294-75-9 2-(3-butenyl)pyridine 
• 98-80-6 phenylboronic acid 
• 1462-75-5 3-phenylpropylmagnesium bromide 
• 1121-60-4 pyridine-2-carbaldehyde 

Relevant academic research and scientific papers

Unlocking the Accessibility of Alkyl Radicals from Boronic Acids through Solvent-Assisted Organophotoredox Activation

Despite their prevalence in organic synthesis, the application of boronic acids (BAs) as alkyl radical precursors in visible-light-assisted photocatalyzed reactions has been limited by their high oxidation potential. This study demonstrates the prominent

Manganese-Catalyzed Hydroarylation of Unactivated Alkenes

Transition-metal-catalyzed hydroarylation of unactivated alkenes with strategic use of remote coordinating functional groups has received significant attention recently to address the issues of both low reactivity and poor selectivity. The bidentate 8-aminoquinoline amide group is the most successfully adopted in unactivated alkenes for Pd and Ni catalysis. We describe the first manganese-catalyzed hydroarylation of unactivated alkenes bearing diverse simple functionalities with arylboronic acids. A series of δ- and γ-arylated amides, ketones, pyridines, and amines was accessed with excellent regioselectivity and in high yields. Hydroalkenylation of unactivated alkenes was also shown to be applicable under this manganese-catalysis regime. The method features earth-abundant manganese catalysis, easily available substrates, broad functional-group tolerance, and excellent regioselective control.

Nickel-Catalyzed Hydrogenolysis and Conjugate Addition of 2-(Hydroxymethyl)pyridines via Organozinc Intermediates

2-Hydroxymethylpyridines undergo nickel-catalyzed hydrogenolysis upon activation with a chlorophosphate. Reactions employ diethylzinc and are proposed to proceed through secondary benzylzinc reagents. Quenching with deuteromethanol provides straightforward incorporation of a deuterium label in the benzylic position. Intramolecular conjugate additions with α,β-unsaturated esters are also demonstrated and support the intermediacy of a benzylzinc complex.