552868-10-7

Basic information

• Product Name: tert-butyl 4-(2-chlorophenoxy)piperidine-1-carboxylate
• Synonyms: tert-butyl 4-(2-chlorophenoxy)piperidine-1-carboxylate;1-Boc-4-(2-chlorophenoxy)piperidine;4-(2-Chlorophenoxy)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester;4-(2-Chlorophenoxy)piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 552868-10-7
• Molecular Formula: C₁₆H₂₂ClNO₃
• Molecular Weight: 311.80378
• Mol File: 552868-10-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 400.8°C at 760 mmHg
• Flash Point: 196.2°C
• Appearance: /
• Density: 1.171
• Vapor Pressure: 1.24E-06mmHg at 25°C
• Refractive Index: 1.533
• PKA: -2.47±0.40(Predicted)
• CAS DataBase Reference: tert-butyl 4-(2-chlorophenoxy)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(2-chlorophenoxy)piperidine-1-carboxylate(552868-10-7)
• EPA Substance Registry System: tert-butyl 4-(2-chlorophenoxy)piperidine-1-carboxylate(552868-10-7)

Safety Data

• Hazardous Substances Data: 552868-10-7(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-(2-chlorophenoxy)piperidine-1-carboxylate is a chemical compound with the chemical formula C15H22ClNO2. It is a piperidine derivative and belongs to the class of organic compounds known as esters. tert-butyl 4-(2-chlorophenoxy)piperidine-1-carboxylate has a molecular weight of 285.79 g/mol and a melting point of 70-72°C. Tert-butyl 4-(2-chlorophenoxy)piperidine-1-carboxylate has potential applications in the pharmaceutical industry as a building block for the synthesis of various biologically active compounds. This chemical may also have potential uses in organic synthesis and medicinal chemistry research.

InChI:InChI=1/C16H22ClNO3/c1-16(2,3)21-15(19)18-10-8-12(9-11-18)20-14-7-5-4-6-13(14)17/h4-7,12H,8-11H2,1-3H3

Upstream product

• 95-57-8 2-monochlorophenol 
• 141699-59-4 1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Downstream Products

• 849107-20-6 4-(2-chloro-phenoxy)-piperidine hydrochloride 
• 245057-65-2 4-(2-chlorophenoxy)piperidine 
• 944808-50-8 C₁₆H₁₈ClN₅O₂ 
• 944808-44-0 C₁₆H₁₅ClN₄O 
• 944808-20-2 6-[4-(2-chlorophenoxy)piperidin-1-yl]pyridazine-3-carboxylic acid 
• 944808-13-3 methyl 6-[4-(2-chlorophenoxy)piperidin-1-yl]pyridazine-3-carboxylate 

Relevant articles and documents

NOVEL ARYLOXYPIPERIDINE PYRAZOLE COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS

Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

MULTIVALENT RAS BINDING COMPOUNDS

Described herein are compounds that modulate Ras signaling, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with altered Ras signaling. Further described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds and methods of using such compounds in the treatment of cell proliferative disorders, including cancer.

NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE

The present invention relates to piperidine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.