55368-75-7

Upstream product

• 55368-74-6 3,5-bis(4-bromophenyl)isoxazole 
• 544-92-3 copper(I) cyanide 
• 3032-92-6 4-cyanophenylacetylene 
• 123476-70-0 4-cyano-N-hydroxy-benzenecarboximidoyl chloride 
• 229308-73-0 1,3-bis(4-cyanophenyl)-2,3-dibromopropan-1-one 
• 52707-54-7 4-cyanobenzaldehyde oxime 
• 105-07-7 4-cyanobenzaldehyde 
• 33170-68-2 1,3-bis-(4-bromo-phenyl)-propane-1,3-dione 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 99-90-1 para-bromoacetophenone 
• 58949-77-2 1,3-bis(4-cyanophenyl)prop-2-en-1-one 

Relevant academic research and scientific papers

Synthesis and in vitro antiprotozoal activities of dicationic 3,5-diphenylisoxazoles

3,5-Bis(4-amidinophenyl)isoxazole (3) - an analogue of 2,5-bis(4- amidinophenyl)furan (furamidine) in which the central furan ring is replaced by isoxazole - and 42 novel analogues were prepared by two general synthetic pathways. The 43 isoxazole derivati

Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles

Novel dicationic 3,5-diphenylisoxazole compounds are described. Synthetic routes to these novel compounds are provided. Several of the compounds displayed in vitro activity versus Trypanosoma brucei brucei and Plasmodium falciparum comparable to that of furamidine. A majority of the novel compounds also were less toxic to VERO cells than furamidine.