55379-06-1

Basic information

• Product Name: 5-methyl-3-phenyl-1,2-benzisothiazole 1,1-dioxide
• Synonyms: 5-methyl-3-phenyl-1,2-benzisothiazole 1,1-dioxide
• CAS NO: 55379-06-1
• Molecular Weight: 257.313
• Mol File: 55379-06-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-methyl-3-phenyl-1,2-benzisothiazole 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-3-phenyl-1,2-benzisothiazole 1,1-dioxide(55379-06-1)
• EPA Substance Registry System: 5-methyl-3-phenyl-1,2-benzisothiazole 1,1-dioxide(55379-06-1)

Safety Data

• Hazardous Substances Data: 55379-06-1(Hazardous Substances Data)

Upstream product

• 4703-19-9 N,N-diphenyl-p-toluenesulfonamide 
• 100-47-0 benzonitrile 
• 98-59-9 p-toluenesulfonyl chloride 
• 100-52-7 benzaldehyde 
• 70-55-3 toluene-4-sulfonamide 
• 81-07-2 saccharin 
• 29083-15-6 5-methylbenzo[d]isothiazol-3(2H)-one 1,1-dioxide 
• 100-58-3 phenylmagnesium bromide 
• 6971-74-0 N-benzoyl-p-toluenesulfonamide 

Downstream Products

• 1609405-75-5 (E)-methyl 3-(2-(5-methyl-1,1-dioxidobenzo[d]isothiazol-3-yl)phenyl)acrylate 
• 1356266-34-6 tert-butyl 8-methyl-9b-phenyl-3,9b-dihydrobenzo[d]pyrrolo[1,2-b]isothiazole-1-carboxylate 5,5-dioxide 
• 1356266-22-2 (E)-tert-butyl 2-(7-methyl-4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2(8bH)-ylidene)acetate 

Relevant articles and documents

Palladium-Catalyzed ortho-Benzoylation of Sulfonamides through C?H Activation: Expedient Synthesis of Cyclic N-Sulfonyl Ketimines

The ortho-carbonylation of sulfonylarenes by non-hazardous aryl aldehydes as a carbonyl precursor was reported. In this method, the sulfonamide group serves as a directing group for C?H activation in the presence of a Pd catalyst under ligand-free conditions. The scope of this strategy has been extended to the one-pot two-step synthesis of cyclic N-sulfonyl ketimines under mild reaction conditions. Our approach could be considered as an alternative by circumventing the use of highly reactive organolithium or Grignard reagents to access a wide range of biologically potent cyclic N-sulfonyl ketimines. (Figure presented.).

Cyclic ketimines as superior electrophiles for NHC-catalyzed homoenolateadditions with broad ScoDe and low catalvst loadinas

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