55420-70-7

Upstream product

• 6287-38-3 3,4-dichlorobenzaldehyde 
• 1439-36-7 1-triphenylphosphoranylidene-2-propanone 
• 102-49-8 3,4-dichlorobenzyl amine 
• 67-64-1 acetone 
• 4202-14-6 dimethyl (2-oxopropyl)phosphonate 

Downstream Products

• 84175-34-8 1-(3,4-dichlorophenyl)-5-morpholin-4-yl-1-penten-3-one hydrochloride 
• 74529-91-2 3-<1-(3,4-Dichlorophenyl)-3-oxobutyl>-1,2-benzoxathiin-4(3H)-one-2,2-dioxide 
• 103976-83-6 C₁₁H₁₁Cl₂N₃S 
• 77921-31-4 4-(3,4-Dichloro-phenyl)-4-ethylsulfanyl-butan-2-one 
• 736150-30-4 4-[(E)-5-(3,4-dichlorophenyl)-3-oxopent-4-enoyl]piperidine-1-carboxylic acid tert-butyl ester 
• 722493-76-7 (E)-6-(3,4-Dichloro-phenyl)-2,4-dioxo-hex-5-enoic acid ethyl ester 
• 159208-15-8 4-(3,4-Dichlorophenyl)-2-methyl-4,6,7,8-tetrahydro-5(1H)-quinolone 
• 27463-42-9 5-(3,4-dichlorophenyl)-1,3-cyclohexanedione 
• 1609385-97-8 (E)-3-(4-(3,4-dichlorophenyl)-2-oxobut-3-en-1-yl)-3-hydroxyindolin-2-one 
• 84175-33-7 1-(3,4-dichlorophenyl)-5-(4-morpholinyl)-3-pentanone hydrochloride 

Relevant academic research and scientific papers

Copper-catalyzed one-pot oxidation-aldol/henry reaction of benzylic amines to α,β-unsaturated methyl ketone/nitro compounds

A novel one-pot synthesis of α,β-unsaturated methyl ketone/nitro compounds from benzylic amines through an oxidation-aldol/Henry reaction is reported. The reaction proceeded well by using MCPBA as oxidant and CuCl 2·2H2O as catalyst. A variety of functionalized α,β-unsaturated methyl ketone/nitro compounds were assembled in moderate yields by application of this catalytic one-pot reaction. Georg Thieme Verlag Stuttgart New York.

PYRIDINE AND PYRIMIDINE DERIVATIVES AS MGIUR2 ANTAGONISTS

The present invention relates to compounds of formula (I), a process for the manufacture thereof, pharmaceutical compositions containing them, and their use for treating CNS disorders:wherein A, B, X, Y, R1, R2, R3 and R4 are as defined in the description and claims.

SUBSTITUTED DIHYDROPYRIDINES AND METHODS OF USE

Compounds are provided that are modulators of the C5a receptor. The compounds are substituted dihydropyridines and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activtation of C5a receptors.

Antiviral 1-aryl-5-amino-1-penten-3-ones

Compounds of the formula STR1 wherein R is H, halo, C1-4 alkyl, C1-4 alkoxy, 3,4-methylenedioxy, CF3, NO2, NH2, N(C1-4 alkyl)2, CN, OH, --S(C1-4 alkyl) or --SO2/

7-Chloro-3-substituted aryl-3,4-dihydro-1,9(2H,10H) and 10 hydroxy acridinedioneimines having antimalarial activity

7-Chloro-3-substituted aryl-3,4-dihydro-1,9-(2H,1OH) and 10-hydroxy-acridinedioneimines and their pharmaceutically acceptable salts and a process for preparing them are disclosed and claimed. The compounds are useful in the treatment of protozoan diseases

The reaction of some nuclear substituted acyclic conjugated styryl ketones and related Mannich bases with ethanethiol.

The second order rate constants for the reaction of ethanethiol with a number of conjugated nuclear-substituted styryl ketones and related Mannich bases in 50percent aqueous acetonitrile was undertaken.Variation of the alkyl group adjacent to the carbonyl