55420-72-9Relevant academic research and scientific papers
Chiral (R)- and (S)-allylic alcohols via a one-pot chemoenzymatic synthesis
Sgalla, Simona,Fabrizi, Giancarlo,Cirilli, Roberto,Macone, Alberto,Bonamore, Alessandra,Boffi, Alberto,Cacchi, Sandro
, p. 2791 - 2796 (2007)
Chiral (R)- and (S)-allylic alcohols with an enantiomeric excess exceeding 99% have been prepared in good to high overall isolated yields through a two-step one-pot chemoenzymatic process based on the palladium-catalyzed Heck reaction of aryl iodides with
Morpholinium trifluoroacetate-catalyzed aldol condensation of acetone with both aromatic and aliphatic aldehydes
Zumbansen, Kristina,Doehring, Arno,List, Benjamin
experimental part, p. 1135 - 1136 (2010/09/05)
We report a highly efficient, general and practical method for the aldol condensation of acetone with aromatic and aliphatic aldehydes, using morpholinium trifluoroacetate as a catalyst.
Use of (S)-5-(2-methylpyrrolidin-2-yl)-1H-tetrazole as a novel and enantioselective organocatalyst for the aldol reaction
Tong, Sok-Teng,Harris, Paul W. R.,Barker, David,Brimble, Margaret A.
, p. 164 - 170 (2008/09/18)
The novel organocatalyst (S)-5-(2-methylpyrrolidin-2-yl)-1H-tetrazole (4) catalyzes the aldol reaction between acetone and various aldehydes with superior enantioselectivity to the existing organocatalysts (S)-proline (1) and (S)-5-(Pyrrolidin-2-yl)-1H-tetrazole (3). Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
