55439-45-7Relevant academic research and scientific papers
Pd(OAc)2 catalyzed C-H activation of 1,3,4-oxadiazoles and their direct oxidative coupling with benzothiazoles and aryl boronic acids using Cu(OAc)2 as an oxidant
Salvanna,Reddy, Gandolla Chinna,Das, Biswanath
supporting information, p. 2220 - 2225 (2013/03/13)
The first direct oxidative coupling of 1,3,4-oxadiazoles with benzothiazoles has been accomplished using Pd(OAc)2 as a catalyst and Cu(OAc)2 as an oxidant. The similar combination of the catalyst and the oxidant has also been applied for direct arylation of 1,3,4-oxadiazoles with aryl boronic acids. Several novel oxadiazole derivatives have been prepared in high yields following both the methods.
Copper(II)-mediated dehydrogenative cross-coupling of heteroarenes
Mao, Zhifeng,Wang, Zhe,Xu, Zhaoqing,Huang, Fei,Yu, Zhengkun,Wang, Rui
supporting information; experimental part, p. 3854 - 3857 (2012/09/11)
Cu(OAc)2-mediated dehydrogenative cross-coupling between two heteroarenes has been realized in the absence of any other additive. A mechanism involving a formal Cu(II) to Cu(0) route by convergent disproportionation of the copper mediator is proposed and has been evidenced by copper mirror formation during the reaction. This synthetic protocol provides a concise and "green" access to unsymmetrical biheteroarenes bearing structural motifs of substantial utility in organic synthesis.
Copper(II)-catalyzed dehydrogenative cross-coupling between two azoles
Qin, Xurong,Feng, Boya,Dong, Jiaxing,Li, Xiaoyu,Xue, Ying,Lan, Jingbo,You, Jingsong
supporting information, p. 7677 - 7683 (2012/11/06)
The copper(II)-catalyzed dehydrogenative coupling between two different azoles for the preparation of unsymmetrical biazoles has been developed. The current catalytic system can effectively control the chemoselectivity for heterocoupling over homocoupling.
Hypervalent iodine mediated synthesis of the heterocyclyl-1,3,4-oxadiazoles
Prakash, Om,Sharma, Vijay,Batra, Hitesh,Rani, Neena,Sharma, Pawan K.,Singh, Shiv
, p. 797 - 800 (2007/10/03)
Oxidation of various heterocyclyl N-acylhydrazones 3a-j with iodobenzene diacetate (IBD) in dichloromethane provides a facile method for the synthesis of heterocyclyl-1,3,4-oxadiazoles 4a-j.
