55439-45-7Relevant academic research and scientific papers
Pd(OAc)2 catalyzed C-H activation of 1,3,4-oxadiazoles and their direct oxidative coupling with benzothiazoles and aryl boronic acids using Cu(OAc)2 as an oxidant
Salvanna,Reddy, Gandolla Chinna,Das, Biswanath
, p. 2220 - 2225 (2013/03/13)
The first direct oxidative coupling of 1,3,4-oxadiazoles with benzothiazoles has been accomplished using Pd(OAc)2 as a catalyst and Cu(OAc)2 as an oxidant. The similar combination of the catalyst and the oxidant has also been applied for direct arylation of 1,3,4-oxadiazoles with aryl boronic acids. Several novel oxadiazole derivatives have been prepared in high yields following both the methods.
Copper(II)-catalyzed dehydrogenative cross-coupling between two azoles
Qin, Xurong,Feng, Boya,Dong, Jiaxing,Li, Xiaoyu,Xue, Ying,Lan, Jingbo,You, Jingsong
supporting information, p. 7677 - 7683 (2012/11/06)
The copper(II)-catalyzed dehydrogenative coupling between two different azoles for the preparation of unsymmetrical biazoles has been developed. The current catalytic system can effectively control the chemoselectivity for heterocoupling over homocoupling.
Copper(II)-mediated dehydrogenative cross-coupling of heteroarenes
Mao, Zhifeng,Wang, Zhe,Xu, Zhaoqing,Huang, Fei,Yu, Zhengkun,Wang, Rui
supporting information; experimental part, p. 3854 - 3857 (2012/09/11)
Cu(OAc)2-mediated dehydrogenative cross-coupling between two heteroarenes has been realized in the absence of any other additive. A mechanism involving a formal Cu(II) to Cu(0) route by convergent disproportionation of the copper mediator is proposed and has been evidenced by copper mirror formation during the reaction. This synthetic protocol provides a concise and "green" access to unsymmetrical biheteroarenes bearing structural motifs of substantial utility in organic synthesis.
Hypervalent iodine mediated synthesis of the heterocyclyl-1,3,4-oxadiazoles
Prakash, Om,Sharma, Vijay,Batra, Hitesh,Rani, Neena,Sharma, Pawan K.,Singh, Shiv
, p. 797 - 800 (2007/10/03)
Oxidation of various heterocyclyl N-acylhydrazones 3a-j with iodobenzene diacetate (IBD) in dichloromethane provides a facile method for the synthesis of heterocyclyl-1,3,4-oxadiazoles 4a-j.
