55442-07-4

Basic information

• Product Name: Custanolide
• CAS NO: 55442-07-4
• Molecular Formula: C₃₄H₄₂N₄O₈S₄
• Molecular Weight: 762.993
• Mol File: 55442-07-4.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Custanolide(CAS DataBase Reference)
• NIST Chemistry Reference: Custanolide(55442-07-4)
• EPA Substance Registry System: Custanolide(55442-07-4)

Safety Data

• Hazardous Substances Data: 55442-07-4(Hazardous Substances Data)

Usage

General Description

Custanolide is a natural compound found in the plant Angelica sinensis, also known as Dong Quai. It is a sesquiterpenoid lactone with a unique chemical structure. Custanolide has been studied for its potential pharmacological and medicinal properties, including anti-inflammatory, anti-tumor, and neuroprotective effects. It is also considered a potential candidate for the treatment of cardiovascular diseases and osteoporosis. Research on custanolide is ongoing, and its potential therapeutic applications make it an intriguing compound for further investigation.

Upstream product

• 4556-90-5 N-(2-bromo-ethyl)-4-methyl-benzenesulfonamide 
• 4403-78-5 ditosylethylenediamine 
• 68-12-2 N,N-dimethyl-formamide 
• 112-24-3 triethylentetramine 
• 98-59-9 p-toluenesulfonyl chloride 
• 7732-18-5 water 

Downstream Products

• 52667-88-6 cyclen tetratosylate 
• 106471-25-4 N³,N⁶,N⁹,N¹²-tetratosyl-3,6,9,12-tetraaza-1,14-tetradecanediol 
• 229031-05-4 6,9,12,15-tetrakis-(toluene-4-sulfonyl)-5,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-6,9,12,15-tetraaza-dibenzo[a,c]cyclohexadecene 
• 60239-18-1 1,4,7,10-tetrakis(carboxymethyl)-1,4,7,10-tetraazacyclododecane 
• 294-90-6 1,4,7,10-tetraazacyclododecan 
• 135839-86-0 14,15-dibromo-2,5,8,11-tetrakis(p-tolylsulphonyl)-1,2,3,4,5,6,7,8,9,10,11,12-dodecahydrobenzo<1,4,7,10>tetraazacyclotetradecine 
• 52601-74-8 N¹,N⁴,N⁷,N¹⁰,N¹³-pentatosyl-1,4,7,10,13-penta-azacyclopentadecane 
• 81582-18-5 1,4,7,10-tetrakis(toluene-p-sulphonyl)-1,4,7,10-tetra-azacyclotetradecane 
• 99892-24-7 (mesyl-1-tetratosyl-4,7,10,13)-pentaaza-1,4,7,10,13-cyclopentadecane 
• 106286-44-6 N²,N⁵,N⁸,N¹¹-tetratosyl-2,5,8,11-tetraaza<12>paracyclophane 
• 1431973-66-8 3,6,9,12-tosyl-1-(6,7)-acridina-3,6,9,12-tetraazatridecaphane 
• 1262589-55-8 2,4,7,10-tetratosyl-2,4,7,10-tetraaza[12]-(2,7)-acridinophane 
• 60147-33-3 4,7,10,13-tetrakis-(toluene-4-sulfonyl)-1-oxa-4,7,10,13-tetraaza-cyclopentadecane 
• 296-35-5 1,4,7,10,13,16-hexaazacyclooctadecane 

Relevant articles and documents

Superalkali-Alkalide Interactions and Ion Pairing in Low-Polarity Solvents

The nature of anionic alkali metals in solution is traditionally thought to be "gaslike"and unperturbed. In contrast to this noninteracting picture, we present experimental and computational data herein that support ion pairing in alkalide solutions. Concentration dependent ionic conductivity, dielectric spectroscopy, and neutron scattering results are consistent with the presence of superalkali-alkalide ion pairs in solution, whose stability and properties have been further investigated by DFT calculations. Our temperature dependent alkali metal NMR measurements reveal that the dynamics of the alkalide species is both reversible and thermally activated suggesting a complicated exchange process for the ion paired species. The results of this study go beyond a picture of alkalides being a "gaslike"anion in solution and highlight the significance of the interaction of the alkalide with its complex countercation (superalkali).

Synthesis of an azacrown template for phosphatidylinositol-4,5-bis(phosphate) recognition

An azacrown system has been developed for selective membrane binding of phosphatidylinositol-4,5-bis(phosphate) recognition. Neutral and cationic forms of the metacyclophane macrocycles have been synthesized by divergent routes in acceptable yields. Such

Preparation of hexaaza and heptaaza macrocycles functionalized with a single aminoalkyl pendant arm

A practical and reproducible route for the preparation of 1,4,7,10,13,16,19-heptaazacyclohenicosane (1), 1,4,7,10,13,16-hexaazacyclooctadecane (2), and 1,4,7,10,13,17-hexaazacycloicosane (3) bearing a single N-(2-amino-ethyl) pendant arm has been develope