55456-48-9

Basic information

• Product Name: 2-Pyrrolidinemethanol, 1-[(4-methylphenyl)sulfonyl]-, (2S)-
• CAS NO: 55456-48-9
• Molecular Formula: C12H17NO3S
• Molecular Weight: 255.338
• Mol File: 55456-48-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-Pyrrolidinemethanol, 1-[(4-methylphenyl)sulfonyl]-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinemethanol, 1-[(4-methylphenyl)sulfonyl]-, (2S)-(55456-48-9)
• EPA Substance Registry System: 2-Pyrrolidinemethanol, 1-[(4-methylphenyl)sulfonyl]-, (2S)-(55456-48-9)

Safety Data

• Hazardous Substances Data: 55456-48-9(Hazardous Substances Data)

Upstream product

• 69610-40-8 N-(tert-butoxycarbonyl)-L-prolinol 
• 98-59-9 p-toluenesulfonyl chloride 
• 67488-65-7 (S)-methyl 1-tosylpyrrolidine-2-carboxylate 
• 147-85-3 L-proline 
• 51077-01-1 L-N-tosyl-proline 
• 54731-09-8 N-tosyl-L-prolyl chloride 
• 654673-64-0 N-(2,2-dimethoxyethyl)-N-(3-iodopropyl)-4-methylbenzenesulfonamide 
• 58754-95-3 N-(2,2-dimethoxyethyl)-p-toluenesulfonamide 
• 654673-69-5 N-(3-iodopropyl)-4-methyl-N-(2-oxoethyl)benzenesulfonamide 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 134513-03-4 (S)-1-(Toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid (1R,2S,5R)-2,5-dimethyl-bicyclo[3.2.0]hept-2-yl ester 
• 134513-03-4 (S)-1-(Toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid (1S,2R,5S)-2,5-dimethyl-bicyclo[3.2.0]hept-2-yl ester 
• 118776-39-9 (2R)-(+)-1-(4-toluenesulphonyl)prolyl chloride 

Downstream Products

• 914082-98-7 Sulfamic acid (S)-1-(toluene-4-sulfonyl)-pyrrolidin-2-ylmethyl ester 
• 74936-95-1 (S)-α-<(R)-pyrrolidin-2-yl>benzyl alcohol 
• 110529-23-2 (αR,2S)-1-methyl-α-phenyl-2-pyrrolidinemethanol 
• 220058-21-9 (R)-1-[(2S)-1-benzylpyrrolidin-2-yl](phenyl)methanol 
• 250589-64-1 (2S,3S)-1-benzyl-3-hydroxy-2-phenylpiperidin 

Relevant articles and documents

O2-Assisted Four-Component Reaction of Vinyl Magnesium Bromide with Chiral N-tert-Butanesulfinyl Imines To Form syn-1,3-Amino Alcohols

An O2-assisted, four-component reaction has been developed to synthesize a wide range of syn-1,3-amino alcohols in one step. The reaction proceeds by oxygenation of vinyl magnesium bromide (component-I) with O2 (component-II) to give

Highly stereoselective syntheses of proline-derived vicinal amino alcohols through grignard addition onto N-tosylprolinal

A highly diastereoselective Grignard addition to N-tosyl-l-prolinal has been developed to deliver a variety of proline-derived vicinal amino alcohols in good to excellent yields with high diastereoselectivities. A similar selectivity was also obtained by using N-tosyl-d-prolinal. The methodology has been applied to the synthesis of medicinally important 3-hydroxy-2-phenylpiperidines.

Copper catalyzed enantioselective intramolecular aminooxygenation of alkenes

-