55469-24-4Relevant academic research and scientific papers
Graphite as an effective catalyst for Friedel-Crafts acylation
Kodomari, Mitsuo,Suzuki, Yoshitada,Yoshida, Kouji
, p. 1567 - 1568 (1997)
Graphite is found to promote Friedel-Crafts acylation of aromatic compounds such as anisole, toluene and o-xylene with acyl halides to give the corresponding acylated products in high yields.
Visible-Light-Driven Epoxyacylation and Hydroacylation of Olefins Using Methylene Blue/Persulfate System in Water
De Souza, Gabriela F. P.,Bonacin, Juliano A.,Salles, Airton G.
, p. 8331 - 8340 (2018/07/21)
A visible-light-driven strategy for hydroacylation and epoxyacylation of olefins in water using methylene blue as photoredox catalyst and persulfate as oxidant is reported. In this unprecedented unified approach, two different transformations are accomplished using only one set of reagents. The method has a broad scope spanning a range of aromatic and aliphatic aldehydes as well as conjugated and nonconjugated olefins to deliver ketones and epoxyketones from abundant and inexpensive chemical feedstocks.
Synthesis of Aryloxy Analogues of Arachidonic Acid via Wittig and Palladium Catalysed Cross-coupling Reactions
Buckle, Derek R.,Fenwick, Ashley E.,Outred, D. James,Rockell, Caroline J. M.
, p. 3144 - 3177 (2007/10/02)
The synthesis of o- and p-phenoxy analogues of arachidonic acid is described.In particular, the Wittig olefination reaction of hydroxy and alkyloxy benzaldehydes has been investigated and the products shown to be highly dependent on the solvent used.E/Z isomer control was difficult to achieve in most cases, although there was a tendency towards Z-isomer formation in dimethyl sulphoxide compared to tetrahydrofuran, particularly for the phenolic compounds.Specific Z-isomer formation was achieved by the partial reduction of alkynes derived from appropriately protected bromophenols via Heck or palladium catalysed cross-coupling reactions.
