55488-94-3

Basic information

• Product Name: Benzeneethanol, 2-ethenyl-
• Synonyms: 2-hydroxyethyl styrene;Benzeneethanol,2-ethenyl
• CAS NO: 55488-94-3
• Molecular Formula: C10H12O
• Molecular Weight: 148.205
• Mol File: 55488-94-3.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzeneethanol, 2-ethenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanol, 2-ethenyl-(55488-94-3)
• EPA Substance Registry System: Benzeneethanol, 2-ethenyl-(55488-94-3)

Safety Data

• Hazardous Substances Data: 55488-94-3(Hazardous Substances Data)

Upstream product

• 1074-16-4 2-bromophenylethyl alcohol 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 130089-19-9 1-bromo-2-(2-methoxyethenyl)benzene 
• 75927-49-0 pinacol vinylboronate 
• 75-21-8 oxirane 
• 2039-88-5 2-bromostyrene 
• 868170-36-9 o-ethenylphenylacetic acid ethyl ester 
• 34824-58-3 2-(2-bromophenyl)-1,3-dioxolan 
• 18698-97-0 ortho-bromophenylacetic acid 
• 75802-18-5 2-(β-hydroxyethyl)benzaldehyde 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 63969-84-6 ethyl 2-formyl-phenyl-acetate 
• 6630-33-7 ortho-bromobenzaldehyde 
• 90320-65-3 Ethyl 2-<2-(1,3-dioxolan-2-yl)phenylacetate> 

Downstream Products

• 401916-57-2 toluene-4-sulfonic acid 2-(2-vinylphenyl)ethyl ester 
• 95798-50-8 1-(2-bromoethyl)-2-vinylbenzene 
• 26164-06-7 1-methyl-3,4-dihydro-1H-2-benzopyran 

Relevant articles and documents

Cascade intramolecular Prins/Friedel–Crafts cyclization for the synthesis of 4-aryltetralin-2-ols and 5-aryltetrahydro-5H-benzo[7]annulen-7-ols

The treatment of 2-(2-vinylphenyl)acetaldehydes or 3-(2-vinylphenyl)propanals with BF3·Et2O results in an intramolecular Prins reaction affording intermediary benzyl carbenium ions, which are then trapped by a variety of electron-ric

Catalytic Asymmetric Synthesis of α-Arylpyrrolidines and Benzo-fused Nitrogen Heterocycles

Herein, we report a practical two-step synthetic route to α-arylpyrrolidines through Suzuki–Miyaura cross-coupling and enantioselective copper-catalyzed intramolecular hydroamination reactions. The excellent stereoselectivity and broad scope for the transformation of substrates with pharmaceutically relevant heteroarenes render this method a practical and versatile approach for pyrrolidine synthesis. Additionally, this intramolecular hydroamination strategy facilitates the asymmetric synthesis of tetrahydroisoquinolines and medium-ring dibenzo-fused nitrogen heterocycles.

Macrocyclic Modulators of the Ghrelin Receptor

The present invention provides novel conformationally-defined macrocyclic compounds that have been demonstrated to be selective modulators of the ghrelin receptor (growth hormone secretagogue receptor, GHS-R1a and subtypes, isoforms and variants thereof). Methods of synthesizing the novel compounds are also described herein. These compounds are useful as agonists of the ghrelin receptor and as medicaments for treatment and prevention of a range of medical conditions including, but not limited to, metabolic and/or endocrine disorders, gastrointestinal disorders, cardiovascular disorders, obesity and obesity-associated disorders, central nervous system disorders, genetic disorders, hyperproliferative disorders and inflammatory disorders.