55528-35-3

Upstream product

• 67-56-1 methanol 
• 2130-77-0 (S)-2-Amino-4-benzyloxycarbonylamino-butyric acid 
• 501-53-1 benzyl chloroformate 
• 100-51-6 benzyl alcohol 
• 226212-75-5 methyl (2S) 2-N-tert-butyloxycarbonyl-4-N-benzyloxycarbonyl-(2,4)-diaminobutyrate 
• 186581-53-3 diazomethane 
• 10270-78-7 N(γ)-Benzyloxycarbonyl-N(α)-(2-nitro-phenylsulfenyl)-L-α,γ-diamino-buttersaeure 

Downstream Products

• 868069-39-0 (2S)-N⁴-benzyloxycarbonyl-1,2,4-triaminobutane 
• 156604-31-8 (2S)-N⁴-benzyloxycarbonyl-N¹,N²-di-tert-butoxycarbonyl-1,2,4-triaminobutane 
• 948912-25-2 methyl (2S)-4-N-benzyloxycarbonyl-2-N-bis(2-ethoxy-2-oxoethyl)-2,4-diaminobutanoate 
• 55478-27-8 (S)-4-benzyloxycarbonylamino-2-[(N-benzyloxycarbonyl-glycyl)-amino]-butyric acid hydrazide 
• 19658-96-9 [(S)-3-[(S)-4-Benzyloxycarbonylamino-2-((R)-2-formylamino-4-methyl-pentanoylamino)-butyrylamino]-3-((1S,2R)-1-hydrazinocarbonyl-2-hydroxy-propylcarbamoyl)-propyl]-carbamic acid benzyl ester 
• 19658-95-8 (2S,3R)-2-{(S)-4-Benzyloxycarbonylamino-2-[(S)-4-benzyloxycarbonylamino-2-((R)-2-formylamino-4-methyl-pentanoylamino)-butyrylamino]-butyrylamino}-3-hydroxy-butyric acid methyl ester 
• 226212-77-7 methyl (2S) 2-N-tosyl-2-N-tert-butylcarboxymethyl-4-N-benzyloxycarbonyl-(2,4)-diaminobutyrate 
• 701197-79-7 (2S) 2-N-tosyl-2-N-tert-butylcarboxymethyl-(2,4)-diaminobutyric acid 
• 110662-68-5 methyl (2S) 2-N-tosyl-4-N-benzyloxycarbonyl-(2,4)-diaminobutyrate 
• 55478-24-5 Z-Gly-N^γ-Z-L-α,γ-Dab-OMe 
• 106195-70-4 - 
• 19658-91-4 (S)-4-Benzyloxycarbonylamino-2-((R)-2-formylamino-4-methyl-pentanoylamino)-butyric acid methyl ester 

Relevant academic research and scientific papers

A new approach to the synthesis of selectively protected (2S)-1,2,4-triaminobutane derivatives

An efficient synthesis of selectively protected (2S)-1,2,4-triaminobutane from L-glutamic acid via (2S)-N4-benzyloxycarbonyl-2,4- diaminobutanamid is described. Georg Thieme Verlag Stuttgart.

RGD mimetics containing a central hydantoin scaffold: α(v)β3 vs α(IIb)β3 selectivity requirements

The synthesis of a series of RGD mimetic α(v)β3 antagonists containing a hydantoin scaffold is shown. The results demonstrate some of the structural requirements for the design of selective α(v)β3 antagonists (vs α(IIb)β3)

Synthesis of perhydrodiazepinones as new putative peptidomimetics

New functionalized 7-membered azaheterocycles (perhydrodiazepinones) have been designed as new scaffolds supposed to mimick peptide γ-turns constrained by an ethylene bridge. They were synthesized by either lactam cyclisation on an aminoacid compound outcoming from a glutamic acid derivative starting material or through an intramolecular Mitsunobu reaction on diaminoalcohol linear precursors. Furthermore, as a new strategy useful for combinatorial chemistry, the second synthesis has been investigated on a soluble polymer support (PEG).