5553-86-6

Basic information

• Product Name: Propanedinitrile, [(4-methylphenyl)methyl]-
• CAS NO: 5553-86-6
• Molecular Formula: C11H10N2
• Molecular Weight: 170.214
• Mol File: 5553-86-6.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Propanedinitrile, [(4-methylphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedinitrile, [(4-methylphenyl)methyl]-(5553-86-6)
• EPA Substance Registry System: Propanedinitrile, [(4-methylphenyl)methyl]-(5553-86-6)

Safety Data

• Hazardous Substances Data: 5553-86-6(Hazardous Substances Data)

Upstream product

• 922-64-5 1,1-dicyanoethylene 
• 108-88-3 toluene 
• 2826-25-7 2-(4-methylbenzylidene)malononitrile 
• 109-77-3 malononitrile 
• 3001-72-7 DBN 
• 104-87-0 4-methyl-benzaldehyde 
• 1149-23-1 diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 95-54-5 1,2-diamino-benzene 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 

Downstream Products

• 21405-60-7 4-methylbenzylmalonic acid 
• 533928-80-2 2-(4-methylbenzyl)-2-methylmalononitrile 
• 1607481-06-0 2-(4-methylbenzyl)-2-phenylmalononitrile 
• 1607831-44-6 C₁₉H₂₄N₆O₄S₂ 
• 1607831-18-4 [8-(4-methylbenzyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrazolo[1,5-a][1,3,5]triazin-7-yl]thiourea 
• 2826-25-7 2-(4-methylbenzylidene)malononitrile 
• 109547-70-8 2,7-Diamino-3-(4-methyl-benzyl)-5-phenyl-4,5-dihydro-pyrazolo[1,5-a]pyrimidine-6-carbonitrile 
• 109547-73-1 2-Amino-3-(4-methyl-benzyl)-7-oxo-5-phenyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrimidine-6-carbonitrile 
• 109547-76-4 2,7-Diamino-3-(4-methyl-benzyl)-5-phenyl-pyrazolo[1,5-a]pyrimidine-6-carbonitrile 

Relevant articles and documents

Catalyst-Free [3 + 3] Annulation/Oxidation of Cyclic Amidines with Activated Olefins: When the Substrate Olefin Is Also an Oxidant

Herein we describe a catalyst-free regioselective [3 + 3] annulation/oxidation reaction of cyclic amidines such as DBU (1,8-diazabicyclo(5.4.0)undec-7-ene) and DBN (1,5-diazabicyclo(4.3.0)non-5-ene) with activated olefins, i.e., 2-arylidenemalononitriles and 2-cyano-3-aryl acrylates, to afford tricyclic 2-pyridones and pyridin-2(1H)-imines, respectively. The mechanism has been proposed based on DFT calculations. In the reaction, the cyclic amidines serve as C,N-bisnucleophiles for the cyclization, while the olefins play a dual role by acting as both reactants and oxidants.

Enhancing catalytic performance via structure core-shell metal-organic frameworks

A core-shell structure metal-organic framework based on the Zr clusters bridging with BDC linkers (UiO-66) as a core-structure and BPYDC linkers (UiO-67-BPY) as a shell-structure was developed (UiO-67-BPY@UiO-66). The combination of several techniques suc

Base-Promoted Cascade Approach for the Preparation of Reduced Knoevenagel Adducts Using Hantzsch Esters as Reducing Agent in Water

A cascade Knoevenagel condensation-reduction approach, which was carried out in water, has been reported. Using Hantzsch esters as reducing agent, under the promotion of base, a variety of reduced Knoevenagel adducts could be easily prepared by direct alkylation of malononitrile, ethyl 2-cyanoacetate, and 2-(4-nitrophenyl)acetonitrile, respectively. Meanwhile, a gram-scale synthesis of the protocol was also realized with excellent isolated yield.