1149-23-1Relevant articles and documents
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Huyser et al.
, p. 4148,4151 (1964)
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Reduction of pyridoxal phosphate (and analogs) by 1,4-dihydropyridine.
Shinkai,Bruice
, p. 8258 - 8258 (1972)
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McMurry,T.B.H.,Richardson,M.C.
, p. 1804 - 1808 (1967)
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Oxidative aromatization of hantzsch 1,4-dihydropyridines by H 2O2/V2o5 at room temperature
Su, Jinlong,Zhang, Cai,Lin, Dan,Duan, Yiqin,Fu, Xiangkai,Mu, Ruizhu
, p. 595 - 600 (2010)
A mild and highly efficient synthetic method was developed for the aromatization of 1,4-dihydropyridines employing H2O2 and 5mol% of V2O5. The reactions were carried out in CH 3CN to give pyridine compounds in excellent yields. Copyright Taylor & Francis Group, LLC.
Slow generation of hydrogen sulfide from sulfane sulfurs and NADH models
Peng, Bo,Liu, Chunrong,Li, Zhen,Day, Jacob J.,Lu, Yun,Lefer, David J.,Xian, Ming
, p. 542 - 545 (2017)
Here we report the model studies of the reactions between NADH models (using HEH and BNAH) and sulfane sulfurs (using polysulfides). Such reactions could lead to the oxidation of NADH models and the production of hydrogen sulfide (H2S). Kinetics of the reaction between BNAH and elemental sulfur S8were determined in ethanol and the second-order rate constant was found to be 0.074?M?1?min?1(at 37?°C) suggesting this is a slow process.
Evaluation of Organic Hydride Donors as Reagents for the Reduction of Carbon Dioxide and Metal-Bound Formates
Elton, Timothy E.,Ball, Graham E.,Bhadbhade, Mohan,Field, Leslie D.,Colbran, Stephen B.
, p. 3972 - 3982 (2018)
A variety of organic hydride donors (OHDs) have been tested as reagents for the transfer of hydride to iron formato complexes in the activation and reduction of carbon dioxide. Theoretical calculations show that the selection of OHD and solvent is crucial when planning systems involving OHD cooperativity. Strong consideration is given to the likelihood that metal centers may deactivate formate to hydride attack, since, in general, the formate group has more resonance stabilization energy when complexed to a metal center compared to an organoformate or formic acid. It is experimentally demonstrated that 1,2-dihydropyridine is not a competent reducing agent for carbon dioxide.
One-pot synthesis of 3-hydroxy-2-oxindole-pyridine hybrids via Hantzsch ester formation, oxidative aromatization and sp3 C–H functionalization using FeWO4 nanoparticles as recyclable heterogeneous catalyst
Paplal, Banoth,Nagaraju, Sakkani,Sathish, Kota,Kashinath, Dhurke
, p. 110 - 115 (2018)
Synthesis of poly-substituted 3-hydroxy-2-oxindole-pyridine hybrids is reported via sp3 C–H bond functionalization as key steps using FeWO4 nanoparticles as reusable heterogeneous catalyst. Formation of Hantzsch ester (DHP) followed by aromatization, and sp3 C–H bond functionalization was achieved using FeWO4 nanoparticles (20 mol%) at 80 °C. Temperature dependent reactivity was observed for mono aldol (at 80 °C) and bis aldol (at 120 °C) products. The catalyst was regenerated and reused up to 6 cycles without losing catalytic activity. The FeWO4 nanoparticles were also used for oxidative aromatization of different DHP derivatives and for the sp3 C–H functionalization of 2-methyl pyridine.
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Huyser,Kahl
, p. 3742 (1970)
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Aqueous CO2fixation: construction of pyridine skeletons in cooperation with ammonium cations
Fan, Weibin,Guo, Shiwei,Huang, Deguang,Li, Yinghua,Xiang, Shiqun,Zhang, Wei
supporting information, p. 7950 - 7955 (2021/10/29)
A simple and green method is explored for the synthesis of fused pyridines by [2 + 2 + 1 + 1] the cycloaddition of ketones with an ammonium cation under a CO2atmosphere. The reactions employed ammonium cation as a nitrogen source and CO2gas as a carbon source in an aqueous solution. Monoethanolamine (MEA) was used as an additive to increase the solubility of CO2in an aqueous solution. The scope and versatility of the method are demonstrated with 38 examples. Products are found to be photosensitive and show potential applications as organic optoelectronic materials. A selectfluor-promoted reaction mechanism is proposed based on the experimental studies. Our work is superior as it is a metal-free system, uses CO2as a carbon source and MEA as an additive in aqueous synthesis.
A Titanium-Catalyzed Reductive α-Desulfonylation
Kern, Christoph,Selau, Jan,Streuff, Jan
supporting information, p. 6178 - 6182 (2021/03/16)
A titanium(III)-catalyzed desulfonylation gives access to functionalized alkyl nitrile building blocks from α-sulfonyl nitriles, circumventing traditional base-mediated α-alkylation conditions and strong single electron donors. The reaction tolerates numerous functional groups including free alcohols, esters, amides, and it can be applied also to the α-desulfonylation of ketones. In addition, a one-pot desulfonylative alkylation is demonstrated. Preliminary mechanistic studies indicate a catalyst-dependent mechanism involving a homolytic C?S cleavage.
