556038-43-8Relevant academic research and scientific papers
Synthesis of regioselectively functionalized pyrenes via transition-metal-catalyzed electrocyclization
Walker, D. Barney,Howgego, Joshua,Davis, Anthony P.
experimental part, p. 3686 - 3692 (2010/12/20)
Transition-metal-catalyzed electrocyclic rearrangement of 2,6-diethynyl-1,1-biphenyl precursors to form polysubstituted pyrenes is described. This method is useful for the preparation of pyrenes with uncommon substitution patterns, and selective integrati
Total synthesis of the duocarmycins
Yamada, Ken,Kurokawa, Toshiki,Tokuyama, Hidetoshi,Fukuyama, Tohru
, p. 6630 - 6631 (2007/10/03)
The total synthesis of (+)-duocarmycin A and SA through a common indoline intermediate is described. The key reactions include selective lithiation of a 2,6-dibromoiodobenzene derivative and diastereoselective addition to a chiral nitroalkene, copper-mediated aryl amination, and addition of aryllithium to azlactones. Copyright
