20455-07-6

Basic information

• Product Name: P-NITROPHENYLMETHANESULFONATE
• Synonyms: P-NITROPHENYLMETHANESULFONATE;Methanesulfonic acid 4-nitrophenyl ester;Methanesulfonic acid p-nitrophenyl ester
• CAS NO: 20455-07-6
• Molecular Formula: C₇H₇NO₅S
• Molecular Weight: 217.19918
• Mol File: 20455-07-6.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 391.2°Cat760mmHg
• Flash Point: 190.4°C
• Appearance: /
• Density: 1.484g/cm³
• Vapor Pressure: 5.64E-06mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: P-NITROPHENYLMETHANESULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: P-NITROPHENYLMETHANESULFONATE(20455-07-6)
• EPA Substance Registry System: P-NITROPHENYLMETHANESULFONATE(20455-07-6)

Safety Data

• Hazardous Substances Data: 20455-07-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H7NO5S/c1-14(11,12)13-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3

Upstream product

• 16156-59-5 phenyl methanesulfonate 
• 100-02-7 4-nitro-phenol 
• 124-63-0 methanesulfonyl chloride 
• 64128-18-3 (CH₃)3SnO(C₆H₄)NO₂ 
• 75-75-2 methanesulfonic acid 
• 104-54-1 3-Phenylpropenol 
• 313959-69-2 1-(cinnamyloxy)-4-nitrobenzene 
• 98-95-3 nitrobenzene 

Downstream Products

• 14609-74-6 p-nitrophenolate 
• 62-50-0 Ethyl methanesulfonate 
• 6625-35-0 methyl 2-(4-nitrophenylsulfanyl)acetate 
• 5950-83-4 2,4'-dinitrodiphenyl ether 
• 619-72-7 4-nitrobenzonitrile 
• 101-63-3 bis(4-nitrophenyl)ether 
• 1394248-15-7 tert-butyl 6-methoxyindoline-1-carboxylate 
• 1428963-59-0 tert-butyl 6-methoxy-7-(4-methoxyphenyl)indoline-1-carboxylate 
• 1428963-60-3 tert-butyl 6-methoxy-7-(4-(trifluoromethyl)phenyl)indoline-1-carboxylate 
• 1428963-61-4 tert-butyl 7-(4-bromophenyl)-6-methoxyindoline-1-carboxylate 
• 1428963-46-5 tert-butyl 7-deuterio-6-methoxyindoline-1-carboxylate 
• 1428963-66-9 tert-butyl 2-methoxy-1-(4-methoxyphenyl)-9H-carbazole-9-carboxylate 
• 191719-02-5 4-amino-3-bromophenyl methanesulfonate 
• 1428963-74-9 3-bromo-4-iodophenyl methanesulfonate 

Relevant articles and documents

Identification of organophosphorus simulants for the development of next-generation detection technologies

Organophosphorus (OP) chemical warfare agents (CWAs) represent an ongoing threat but the understandable widespread prohibition of their use places limitations on the development of technologies to counter the effects of any OP CWA release. Herein, we describe new, accessible methods for the identification of appropriate molecular simulants to mimic the hydrogen bond accepting capacity of the PO moiety, common to every member of this class of CWAs. Using the predictive methodologies developed herein, we have identified OP CWA hydrogen bond acceptor simulants for soman and sarin. It is hoped that the effective use of these physical property specific simulants will aid future countermeasure developments.

ALKYNE COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS

Provided are compounds of formula (Ia) and pharmaceutically acceptable salts thereof, wherein A, B, R 1, R 2, m and n are as defined herein, which are active as inhibitors of S-Nitrosoglutathione reductase (GSNOR). These compounds prevent, inhibit, or suppress the action of GSNOR and are therefore useful in the treatment of GSNOR mediated diseases, disorders, syndromes or conditions such as, e.g., pulmonary hypertension, acute respiratory distress syndrome (ARDS), asthma, bronchospasm, cough, pneumonia, pulmonary fibrosis, interstitial lung diseases, cystic fibrosis and chronic obstructive pulmonary disease (COPD).

Synthesis of substituted indoline and carbazole by benzyne-mediated cyclization-functionalization

A benzyne-mediated synthesis of substituted indolines and carbazoles was developed. The reaction includes generation of benzyne using Mg(TMP) 2·2LiCl as a base, cyclization, and trapping the resulting organomagnesium intermediate with an electr