55605-84-0Relevant academic research and scientific papers
Ru-Catalyzed Deoxygenative Regioselective C8-H Arylation of Quinoline N-Oxides
Kim, Jinwoo,Kim, Suhyeon,Kim, Dongwook,Chang, Sukbok
, p. 13150 - 13158 (2019)
Regioselective C-H functionalization on quinolines is of high interest to lead to value-added products. Herein, we describe the development of Ru-catalyzed deoxygenative regioselective C8 arylation of quinoline N-oxides with arylboronic esters. Mechanistic studies revealed that it proceeds in a tandem process of arylation and then deoxygenation, wherein both steps were found to be catalytic with the ruthenium species.
