55685-70-6

Upstream product

• 67-56-1 methanol 
• 36458-91-0 2,2,2-trichloro-1-(4-methoxyphenyl)ethan-1-one 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 121-98-2 methyl 4-methoxybenzoate 
• 123-11-5 4-methoxy-benzaldehyde 

Relevant academic research and scientific papers

Transition-metal-free transformation of aryl bromides into aromatic esters and amides via aryl trichloromethyl ketones

A variety of aryl bromides have been treated with Mg and then chloral, followed by tBuOCl and subsequently alcohols or amines to produce the corresponding aromatic esters or amides in good yields via the formation of aryl trichloromethyl ketones as intermediates. These reactions are examples of a transition-metal-free one-pot preparation of aromatic esters and amides from aryl bromides. Aryl bromides have been treated with Mg and then chloral, followed by tBuOCl or tBuOCl with I2 as an additive, and subsequently alcohols or amines to form the corresponding aromatic esters and aromatic amides via aryl trichloromethyl ketones as intermediates. Copyright

PTFE supported gold nanoparticles as photocatalysts for oxidative esterification of aldehydes

Homogeneous, small gold nanoparticles (d = 1.87 nm) have been prepared by photochemical reduction of HAuCl4 in the presence of Irgacure 2959 under high power UV irradiation at 365 nm produced by a LED source. These particles have been deposited on PTFE microbeads (d = 200 μm) and evaluated for the catalysis of the oxidative esterification of aldehydes in the presence of H2O2. Under green light (λ ≈ 530 nm) and repeated addition of H2O2, the catalytic system is accelerated and achieves complete conversions in minutes. Furthermore the catalyst can be recycled ten times consecutively without any activity loss by adding a step for AuNP recycling. The mechanism of the reaction follows a zero rate order, and Hammett free energy relationships for substituted benzaldehydes afforded a positive ρ value (ρ = 2.35) demonstrating that the initial hemiacetalisation equilibrium (ρ = 2.31) is the rate determining step. Kinetics data are in agreement with an Eley-Rideal type mechanism and permits proposing a reaction mechanism.