55703-81-6Relevant academic research and scientific papers
Anti-inflammatory compound and application thereof
-
Paragraph 0041-0045, (2020/06/17)
The invention relates to the technical field of chemical cosmetics or medicines, and concretely relates to an anti-inflammatory compound and an application thereof. By preparing a series of compoundswith an anti-inflammatory function, the obtained anti-inflammatory compound can be used for preparing cosmetic reagents or pharmaceutical reagents, and the cosmetic reagents and the pharmaceutical reagents are not specifically limited, for example, the cosmetics can be a smoothing toner, a nutritional toner, a massage cream, a nutritional cream, a mask, an emollient, a gel, and gel or shower gel shampoo and other washing type cosmetics, and can also be a pharmaceutical preparation product similar to lotion and cream, ointment, cream, plaster or spray and the like. The anti-inflammatory compound also can be used by sensitive skins, and also can be added into infant and child cosmetics to reduce irritation.
Total synthesis of (±)-Taiwaniaquinol B via a domino intramolecular Friedel-Crafts acylation/carbonyl α-tert-alkylation reaction
Fillion, Eric,Fishlock, Dan
, p. 13144 - 13145 (2007/10/03)
The first synthesis of taiwaniaquinol B, a 6-nor-5(6→7)abeoabietane-type diterpenoid exhibiting the uncommon fused 6-5-6 tricyclic carbon skeleton, was accomplished in 15 steps. A Lewis acid-promoted tandem intramolecular Friedel-Crafts/carbonyl α-tert-alkylation reaction was exploited as the core strategy for the synthesis of the sterically congested 1-indanone-containing tricyclic structure. This multiple carbon-carbon bond forming reaction exploits the unique reactivity of Meldrum's acid. The facile precursor synthesis makes this a useful methodology for the expedient modification and assembly of sterically congested 1-indanone-containing ring systems. Copyright
