55712-24-8Relevant academic research and scientific papers
One-Pot Synthesis of 4-Quinolone via Iron-Catalyzed Oxidative Coupling of Alcohol and Methyl Arene
Lee, Seok Beom,Jang, Yoonkyung,Ahn, Jiwon,Chun, Simin,Oh, Dong-Chan,Hong, Suckchang
, p. 8382 - 8386 (2020/11/18)
Herein, we describe the iron(III)-catalyzed oxidative coupling of alcohol/methyl arene with 2-amino phenyl ketone to synthesize 4-quinolone. Alcohols and methyl arenes are oxidized to the aldehyde in the presence of an iron catalyst and di-tert-butyl peroxide, followed by a tandem process, condensation with amine/Mannich-type cyclization/oxidation, to complete the 4-quinolone ring. This method tolerates various kinds of functional groups and provides a direct approach to the synthesis of 4-quinolones from less functionalized substrates.
Transition-Metal-Free C-3 Arylation of Quinoline-4-ones with Arylhydrazines
Ravi, Makthala,Chauhan, Parul,Kant, Ruchir,Shukla, Sanjeev K.,Yadav, Prem. P.
, p. 5369 - 5376 (2015/05/27)
(Chemical Equation Presented) A transition-metal-free C-3-arylation of quinolin-4-ones in the presence of base has been achieved by using arylhydrazines as aryl radical source and air as oxidant. The reaction proceeds smoothly at room temperature and does
2-aryl-4-chloro-3-iodoquinolines as substrates for the synthesis of 2,3-diaryl-4-methoxyquinolines
Mphahlele, Malose J.,Mtshemla, Vathiswa
experimental part, p. 437 - 440 (2009/08/15)
Sequential functionalisation of 2-aryl-4-chloro-3-iodoquinolines via palladium-catalysed cross-coupling with phenylboronic acid followed by displacement of the 4-chloro atom from the resulting 2,3-diaryl-4- chloroquinolines with methoxide ion yielded 2,3-
