55805-17-9

Basic information

• Product Name: Benzoic acid, 3-(1,1-difluoroethyl)-
• CAS NO: 55805-17-9
• Molecular Formula: C9H8F2O2
• Molecular Weight: 186.158
• Mol File: 55805-17-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-(1,1-difluoroethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-(1,1-difluoroethyl)-(55805-17-9)
• EPA Substance Registry System: Benzoic acid, 3-(1,1-difluoroethyl)-(55805-17-9)

Safety Data

• Hazardous Substances Data: 55805-17-9(Hazardous Substances Data)

Upstream product

• 445303-70-8 1-Bromo-3-(1,1-difluoro-ethyl)-benzene 
• 124-38-9 carbon dioxide 
• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 878745-29-0 methyl 3-(1,1-difluoroethyl)benzoate 
• 21860-07-1 methyl 3-acetylbenzoate 
• 6136-68-1 3-acethylbenzonitrile 
• 55805-06-6 3-(1,1-difluoroethyl)benzonitrile 

Relevant articles and documents

Scalable Approach to Fluorinated Heterocycles with Sulfur Tetrafluoride (SF4)

A general approach to fluorinated (hetero)aromatic derivatives is elaborated. The key reaction is a deoxofluorination of substituted acetophenones with sulfur tetrafluoride (SF4). In contrast to previous deoxofluorination methods, this transformation is fast, scalable (up to 70 g), and high-yielding. More than 100 novel or previously hardly accessible fluorinated heterocycles, interesting for medicinal chemistry and agrochemistry, were synthesized.

PYRIDINE CARBOXAMIDE DERIVATIVES FOR USE AS ANTICANCER AGENTS

The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof of the formula (I): (A chemical formula should be inserted here - please see paper copy enclosed herewith) (I) which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.

Process for producing fluorinated organic compounds containing a difluoromethylene group from compounds comprising at least one carbonyl function

A novel process for producing fluorinated organic compounds containing a difluoromethylene group, essentially characterized by reacting organic compounds containing a carbonyl function with molybdenum hexafluoride at room temperature and under atmospheric