5586-90-3

Basic information

• Product Name: N-(3-chloropropyl)-N-phenylaniline
• Synonyms: N-(3-chloropropyl)-N-phenylaniline
• CAS NO: 5586-90-3
• Molecular Weight: 245.752
• Mol File: 5586-90-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(3-chloropropyl)-N-phenylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-chloropropyl)-N-phenylaniline(5586-90-3)
• EPA Substance Registry System: N-(3-chloropropyl)-N-phenylaniline(5586-90-3)

Safety Data

• Hazardous Substances Data: 5586-90-3(Hazardous Substances Data)

Upstream product

• 26064-89-1 3-chloro-N,N-diphenyl-propionamide 
• 122-39-4 diphenylamine 
• 109-70-6 1.3-chlorobromopropane 

Downstream Products

• 95017-53-1 1-[1-(3-Diphenylamino-propyl)-piperidin-4-yl]-1,3-dihydro-benzoimidazol-2-one 

Relevant articles and documents

Synergetic Effect of Monomer Functional Group Coordination in Catalytic Insertion Polymerization

PhS- and PhNH-functionalized dienes are copolymerized efficiently with butadiene to stereoregular copolymers by [(mesitylene)Ni(allyl)][BArF4] (Ni-1). Overall polymerization rates and comonomer incorporations depend strongly on the l

1-piperidines and Related Compounds, Potential Antipsychotic Agents with Low Cataleptogenic Profiles

On the basis of a structural model of the postsynaptic dopaminergic antagonist pharmacophore, a series of 1-piperidines and related compounds was synthesized and evaluated for potential antipsychotic activity.For a rapid measure of activity, the target compounds were initially screened in vitro for inhibition of haloperidol binding and in vivo in a test of locomotor activity.Behavioral efficacy of compounds identified from the initial screens was more accurately measured in rats by using a suppression of high base-line medial forebrain bundle self-stimulation test model.The propensity of these compounds for causing extrapyramidal side effects was evaluated by using a rat catalepsy method.On the basis of these test models, we have shown that the methine carbon of the 1-(4,4-diarylbutyl)piperidines can be advantageously replaced with a nitrogen atom.The 1-piperidines were less cataleptic than the corresponding 1-(4,4-diarylbutyl)piperidines.The compounds with the widest separation between efficacious dose and cataleptic dose are 8-propyl>-1-phenyl-1,3,8-triazaspirodecan-4-one (6), 1-propyl>-4-piperidinyl>-1,3-dihydro-2H-benzimidazol-2-one (11), 1-propyl>-1,2,3,6-tetrahydro-4-pyridinyl>-1,3-dihydro-2H-benzimidazol-2-one (22), and 1-propyl>-4-(2-methoxyphenyl)piperazine (26).