55951-74-1

Usage

InChI:InChI=1/C15H20O4/c1-3-18-14(16)10-13(11-15(17)19-4-2)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11H2,1-2H3

Upstream product

• 100-52-7 benzaldehyde 
• 2025-40-3 ethyl benzylidenecyanoacetate 
• 6768-26-9 2-phenyl-1,1,3,3-tetraethoxycarbonylpropane 
• 4165-96-2 3-phenylglutaric acid 

Downstream Products

• 859981-75-2 3-phenyl-glutaric acid bis-pentylamide 
• 859981-72-9 3-phenyl-glutaric acid bis-phenethylamide 
• 61198-49-0 (S)-4-phenyltetrahydro-2H-pyran-2-one 
• 71302-21-1 (4R)-4-phenyltetrahydro-2H-pyran-2-one 
• 536972-25-5 5-(acetyloxy)-3-phenylpentanoic acid 
• 131906-17-7 methyl 5-hydroxy-3-phenylpentanoate 
• 1263799-44-5 5-(acetyloxy)-3-phenylpentyl 3,3,3-trifluoro-2-methoxy-2-phenylpropanoate 
• 1263798-71-5 (R)-5-hydroxy-3-phenylpentyl acetate 
• 153363-11-2 (S)-5-hydroxy-3-phenylpentyl acetate 
• 1263798-38-4 (+/-)-5-hydroxy-3-phenylpentyl acetate 
• 1263798-11-3 3-phenylpentane-1,5-diyl diacetate 
• 1263798-88-4 5-(acetyloxy)-3-phenylpentanoic acid 
• 71642-55-2 1-phenethyl-4-phenyl-piperidine 
• 19015-37-3 1-(phenylmethyl)-4-phenylpiperidine 

Relevant academic research and scientific papers

Hydrogen-Bonding Catalyzed Ring-Closing C?O/C?O Metathesis of Aliphatic Ethers over Ionic Liquid under Metal-Free Conditions

O-heterocycles have wide applications, and their efficient and green synthesis is very interesting. Herein, we report hydrogen-bonding catalyzed ring-closing metathesis of aliphatic ethers to O-heterocycles over ionic liquid (IL) catalyst under metal- and solvent-free conditions. The IL 1-butylsulfonate-3-methylimidazolium trifluoromethanesulfonate ([SO3H-BMIm][OTf]) is discovered to show outstanding performance, better than the reported catalysts. An interface effect plays an important role in mediating the reaction rate due to the immiscibility between the products and the IL catalyst, and the products can be spontaneously separated. NMR analysis and DFT calculation suggest that a pair of cation and anion of [SO3H-BMIm][OTf] could form three strong H-bonds with an ether molecule, which catalyze the ether transformation via a cyclic oxonium intermediate. A series of O-heterocycles including tetrahydrofurans, tetrahydropyrans, morpholines and dioxane can be obtained from their corresponding ethers in excellent yields (e.g., >99 %). This work opens an efficient and metal-free way to produce O-heterocycles from aliphatic ethers.

A phosphine-free iron complex-catalyzed synthesis of cycloalkanes: Via the borrowing hydrogen strategy

Herein we report a diaminocyclopentadienone iron tricarbonyl complex catalyzed synthesis of substituted cyclopentane, cyclohexane and cycloheptane compounds using the borrowing hydrogen strategy in the presence of various substituted primary and secondary 1,n diols as alkylating reagents. Deuterium labeling experiments confirm that the diols were the hydride source in this cascade process. This journal is