829-27-6

Basic information

• Product Name: 1,5-Pentanediol, 3-phenyl-
• CAS NO: 829-27-6
• Molecular Formula: C11H16O2
• Molecular Weight: 180.247
• Mol File: 829-27-6.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1,5-Pentanediol, 3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-Pentanediol, 3-phenyl-(829-27-6)
• EPA Substance Registry System: 1,5-Pentanediol, 3-phenyl-(829-27-6)

Safety Data

• Hazardous Substances Data: 829-27-6(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Faint

Applications

a. Production of cosmetics and personal care products
b. Pharmaceutical industry

Functions

a. Solvent
b. Humectant
c. Viscosity controlling agent
d. Antimicrobial properties (used as a preservative)

Skin benefits

Attracts and retains moisture, hydrates and softens the skin

Usage in products

Moisturizers, lotions, and creams

Additional applications

a. Insect repellents
b. Intermediate in the synthesis of other organic compounds

Upstream product

• 100-52-7 benzaldehyde 
• 6768-26-9 2-phenyl-1,1,3,3-tetraethoxycarbonylpropane 
• 19006-47-4 dimethyl 3-phenylpentanedioate 
• 4165-96-2 3-phenylglutaric acid 
• 55951-74-1 diethyl 3-phenylpentanedioate 
• 2025-40-3 ethyl benzylidenecyanoacetate 

Downstream Products

• 143867-02-1 1-pentyl-4-phenylpiperidine 
• 771-99-3 4-phenylpiperidine 
• 2050-92-2 Di-n-amylamine 
• 225376-91-0 3-phenyl-5-(tetrahydro-pyran-2-yloxy)-pentan-1-ol 
• 20638-52-2 4-phenyltetrahydro-2H-pyran 
• 862-71-5 3-phenyl-1,5-bis-phenylcarbamoyloxy-pentane 
• 27070-24-2 (3-bromo-1-(2-bromoethyl)-propyl)benzene 
• 71280-25-6 3-Cyclohexyl-pentane-1,5-diol 
• 1466-73-5 trans-4-phenylcyclohexanecarboxylic acid 
• 37810-46-1 trans-4-(phenyl)cyclohexane-1-carbaldehyde 
• 87073-90-3 ((1r,4r)-4-phenylcyclohexyl)methanol 

Relevant articles and documents

A phosphine-free iron complex-catalyzed synthesis of cycloalkanes: Via the borrowing hydrogen strategy

Herein we report a diaminocyclopentadienone iron tricarbonyl complex catalyzed synthesis of substituted cyclopentane, cyclohexane and cycloheptane compounds using the borrowing hydrogen strategy in the presence of various substituted primary and secondary 1,n diols as alkylating reagents. Deuterium labeling experiments confirm that the diols were the hydride source in this cascade process. This journal is

Direct Synthesis of Cycloalkanes from Diols and Secondary Alcohols or Ketones Using a Homogeneous Manganese Catalyst

A method for the synthesis of substituted cycloalkanes was developed using diols and secondary alcohols or ketones via a cascade hydrogen borrowing sequence. A non-noble and air-stable manganese catalyst (2 mol %) was used to perform this transformation. Various substituted 1,5-pentanediols (3-4 equiv) and substituted secondary alcohols (1 equiv) were investigated to prepare a collection of substituted cyclohexanes in a diastereoselective fashion. Similarly, cyclopentane, cyclohexane, and cycloheptane rings were constructed from substituted 1,4-butanediol, 1,5-pentanediol, and 1,6-hexanediol, and sterically hindered ketones following a (4 + 1), (5 + 1), and (6 + 1) strategy, respectively. This reaction provides an atom economic methodology to construct two C-C bonds at a single carbon center generating high-value cycloalkanes from readily available alcohols as feedstock using an earth-abundant metal catalyst.

N-[3-(2-CARBOXYETHYL)PHENYL]PIPERIDIN-1-YLACETAMIDE DERIVATIVES AND USE THEREOF AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE

The present application relates to novel substituted 2-(piperidin-1-yl)acetamide derivatives, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of cardiovascular diseases.