55953-49-6Relevant academic research and scientific papers
The preferred conformation of α-fluoroamides
Banks, John W.,Batsanov, Andrei S.,Howard, Judith A. K.,O'Hagan, David,Rzepa, Henry S.,Martin-Santamaria, Sonsoles
, p. 2409 - 2411 (1999)
X-Ray structures of two α-fluoroamide derivatives show the O=C-C-F moiety tending towards a trans planar conformation, for which ab initio calculations suggest a deep (up to 8 kcal mol-1) potential minimum.
The influence of molecular structure and crystallization time on the efficiency of diastereoisomeric salt forming resolutions
Palovics, Emese,Schindler, Jozsef,Faigl, Ferenc,Fogassy, Elemer
experimental part, p. 2429 - 2434 (2010/12/25)
Reciprocal resolutions between compounds (racemates and enantiomers) with similar structures have been examined. Amongst structurally similar compounds (so called relative structures) several N-acyl amino acids and amino acid esters were investigated. A part of the resolving agent or the racemic compound could be replaced by an achiral compound with a relative structure and an additive could occasionally improve significantly the efficiency of the resolution. Both the kinetic and the thermodynamic controls were observed as governing factors of the reciprocal resolutions.
GLYCEROL DERIVATIVE
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Page/Page column 29-31, (2008/06/13)
(wherein R represents a residue comprising a reactive group or a group capable of being transformed into the reactive group; n represents an integer of 3 or more; and X represents a residue capable of having the following structure by n in number: R1
Method for the N-acylation of aminocarboxylic acids
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, (2008/06/13)
A process is disclosed for the prparation of an acylated aminocarboxylic acid which comprises contacting an aminocarboxylic acid, its alkali metal or alkaline earth metal salt with a low alkyl carboxylic acid ester of the formula wherein R1 represents hydrogen or a straight-chain or branched or cyclic hydrocarbon moiety of 1 to 30 carbon atoms, which can be substituted if desired, and wherein R2 represents a straight-chain, branched or cyclic hydrocarbon moiety of 1 to 8 carbon atoms in the presence of an alkali metal or alkaline earth metal alcoholate.
Resolution of N-acyl-DL (+)-phenylalanines
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, (2008/06/13)
The treatment of N-acyl-DL(+)-phenylalanines with D(-)-2-(2,5-dimethylbenzylamino)-1-butanol results in the formation of the D(-)-2-(2,5-dimethylbenzylamino)-1-butanol salt which is obtained as a crystallizate of the N-acyl-L(+)-phenylalanine and from which the desired N-acyl-L(+)-phenylalanine, an intermediate useful for the preparation of artificial sweetening agents, can be recovered.
