56058-23-2

Upstream product

• 166885-99-0 dimethylketene diethylacetal 
• 3282-32-4 2-diazo-acetophenone 
• 56058-22-1 1-Benzoyl-2,2-dichlorocyclopropane 
• 124-41-4 sodium methylate 
• 300-57-2 allylbenzene 
• 939-78-6 2-benzyl-1,1-dichlorocyclopropane 
• 138723-90-7 2,5-dihydro-2,2-dimethoxy-5,5-dimethyl-1,3,4-oxadiazole 
• 768-03-6 Phenyl vinyl ketone 

Downstream Products

• 56795-82-5 5-phenyl-2-methoxyfurane 
• 19522-28-2 (Z)-4-oxo-4-phenyl-but-2-enoic acid methyl ester 
• 101028-25-5 methyl cis-2,3-epoxy-4-oxo-4-phenylbutanoate 
• 25333-24-8 3-benzoylpropionic acid methyl ester 

Relevant academic research and scientific papers

O-Heterocycles from Unsaturated Carbonyls and Dimethoxycarbene

The (4+1)-annulation of dimethoxycarbene with readily accessible α,β-unsaturated carbonyls gives cyclic orthoesters, which can then be converted in just a few steps to other O-heterocycles, including methoxyfurans, furanones, and furans.

Reaction of Ketenes. Part 18. Catalysed Reactions between α-Diazocarbonyl Compounds and Ketene Acetals

In the presence of copper powder of Cu(acac)2, ethyl diazoacetate reacts with dialkylketene acetals to give cyclopropanes (2) whilst with ketene acetals having at least one hydrogen atom at position 2 both cyclopropanes (2) and butenoates (3) are formed.Noteworthy in these reactions is the fact that the α-diazoester fails to give dihydrofurans (1), which are the only reaction products when α-diazoketones are the employed α-diazocarbonyl compounds.The results can be rationalized on the basis of the intermediacy of a species in which α-diazocarbonyl compound, catalyst, and ketene acetal are involved.