56107-77-8Relevant academic research and scientific papers
Iridium-catalyzed C-H amidation of: S -tetrazines
Xiong, Huan,Gu, Yuang,Zhang, Shuning,Lu, Fengping,Ji, Qun,Liu, Lili,Ma, Peixiang,Yang, Guang,Hou, Wei,Xu, Hongtao
, p. 4692 - 4695 (2020/05/22)
An efficient, selective and scalable C-H amidation of s-tetrazines under iridium(III) catalysis is reported. This reaction features a broad substrate scope, high functional group tolerance, and air and water tolerance. This reaction also shows great potential for the rapid preparation of tri- and tetra-functional building blocks, which can be applied either in bioconjugation or synthesis of DNA-encoded library.
Synthesis, structures of some unsymmetrical 3,6-disubstituted-1,2,4,5- tetrazines
Hu, Wei-Xiao,Xu, Feng
experimental part, p. 1745 - 1750 (2009/05/31)
(Chemical Equation Presented) A series of new unsymmetrical 3-phenyl-6-benzyl-1,2,4,5-tetrazine derivatives 10a-i were synthesized and characterized by IR, NMR, MS, and element analysis. The structures of 4a, 10c, 10d and 10h were analyzed by X-ray crystallography, which had intermolecular C-H...N, C-H...Cl, C-H...Π and Π...Π H interactions.
