561277-15-4

Basic information

• Product Name: N-(3-benzyloxy-4-methoxy-phenyl)-N'-(4-methyl-3-trifluoromethyl-phenyl)-ethane-1,2-diamine
• CAS NO: 561277-15-4
• Molecular Weight: 430.47
• Mol File: 561277-15-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-benzyloxy-4-methoxy-phenyl)-N'-(4-methyl-3-trifluoromethyl-phenyl)-ethane-1,2-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-benzyloxy-4-methoxy-phenyl)-N'-(4-methyl-3-trifluoromethyl-phenyl)-ethane-1,2-diamine(561277-15-4)
• EPA Substance Registry System: N-(3-benzyloxy-4-methoxy-phenyl)-N'-(4-methyl-3-trifluoromethyl-phenyl)-ethane-1,2-diamine(561277-15-4)

Safety Data

• Hazardous Substances Data: 561277-15-4(Hazardous Substances Data)

Upstream product

• 61324-40-1 3-benzyloxy-4-methoxybenzeneamine 
• 636-93-1 5-nitroguaiacol 
• 75167-86-1 2-(benzyloxy)-1-methoxy-4-nitrobenzene 
• 65934-74-9 3-(trifluoromethyl)-4-methylaniline 
• 100-39-0 benzyl bromide 
• 561277-06-3 2-(4-methyl-3-trifluoromethyl-phenylamino)-ethanol 

Downstream Products

• 561277-27-8 1-(3-hydroxy-4-methoxy-phenyl)-3-(4-methyl-3-trifluoromethyl-phenyl)-imidazolidin-2-one 
• 561277-24-5 1-(3-benzyloxy-4-methoxy-phenyl)-3-(4-methyl-3-trifluoromethyl-phenyl)-imidazolidin-2-one 

Relevant articles and documents

A series of bisaryl imidazolidin-2-ones has shown to be selective and orally active 5-HT2C receptor antagonists

Bisaryl cyclic ureas have been identified as high affinity 5-HT 2C receptor antagonists with selectivity over 5-HT2A and 5-HT2B. Compounds such as 8 and 22 have shown oral activity in a centrally mediated pharmacodynamic model of 5-HT2C function in rodents.