56145-24-5

Basic information

• Product Name: Proline, 2-methyl-5-oxo-, methyl ester (9CI)
• Synonyms: Proline, 2-methyl-5-oxo-, methyl ester (9CI);2-Methyl-5-oxo-2-pyrrolidinecarboxylic acid methyl ester;2-Methyl-5-oxo-Proline Methyl ester;2-Methyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester
• CAS NO: 56145-24-5
• Molecular Formula: C7H11NO3
• Molecular Weight: 157.16714
• Product Categories: PYRROLE
• Mol File: 56145-24-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 53-54 °C
• Boiling Point: 105-110 °C(Press: 0.5 Torr)
• Appearance: /
• Density: 1.144±0.06 g/cm3(Predicted)
• PKA: 14.72±0.40(Predicted)
• CAS DataBase Reference: Proline, 2-methyl-5-oxo-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Proline, 2-methyl-5-oxo-, methyl ester (9CI)(56145-24-5)
• EPA Substance Registry System: Proline, 2-methyl-5-oxo-, methyl ester (9CI)(56145-24-5)

Safety Data

• Hazardous Substances Data: 56145-24-5(Hazardous Substances Data)

Upstream product

• 113747-75-4 methyl 2-methyl-2-nitro-1,5-pentanedicarboxylate 
• 62013-44-9 methyl 2-nitro-propionate 
• 292638-85-8 acrylic acid methyl ester 
• 123-76-2 levulinic acid 
• 67-56-1 methanol 
• 938074-86-3 C₁₆H₂₂N₂O₄ 
• 64298-96-0 dimethyl 2-(benzylideneamino)-2-methylpentanedioate 

Downstream Products

• 15438-71-8 1-(hydroxymethyl)-2-pyrrolidinone 

Relevant articles and documents

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This application describes compounds useful as anti-microbial agents, including as antibacterial, disinfectant, antifungal, germicidal or antiviral agents.

Solventless lactam synthesis by intramolecular cyclizations of α-iminoester derivatives under microwave irradiation

We have previously reported a new synthesis of amides from esters and amines under microwave irradiation, offering much higher yields than those achieved with conventional heating [1]. We have now extended these studies to the ring closure of neat iminoes

ALKYLATION OF SHIFF BASE ANIONS WITH ω-HALOGENO ESTERS: A LACTAM SYNTHESIS.

Imine anions of α-aminoesters, obtained from NaH/DMSO are alkylated with ω-halogenoesters.Thermolysis of the alkylated compounds lead to functionnalized lactams.