5619-82-9Relevant academic research and scientific papers
Reductive alkylation of active methylene compounds with carbonyl derivatives, calcium hydride and a heterogeneous catalyst
Guyon, Carole,Duclos, Marie-Christine,Sutter, Marc,Métay, Estelle,Lemaire, Marc
, p. 7067 - 7075 (2015/06/25)
A one-pot two-step reaction (Knoevenagel condensation - reduction of the double bond) has been developed using calcium hydride as a reductant in the presence of a supported noble metal catalyst. The reaction between carbonyl compounds and active methylene
Electrooxidation of malonate and acetylacetate derivatives in the presence of halide ions
Okimoto, Mitsuhiro,Takahashi, Yukio
, p. 2215 - 2219 (2007/10/03)
β-Dicarbonyl compounds, such as dimethyl malonate derivatives and methyl acetoacetate derivatives, were electrooxidized in methanol in the presence of halogen ions to afford the corresponding dimethyl α-halomalonates and methyl α-halocarboxylates. Electrooxidation of bis(β-dimethoxycarbonyl) derivatives similarly afforded cyclic compounds and dihalides.
Clay-mediated Synthesis of gem-Bis(alkoxycarbonyl) Alkenes under Microwave Irradiation
Ayoubi, Sahar Abdallah-El,Texier-Boullet, Francoise
, p. 208 - 209 (2007/10/03)
Diethyl and dimethyl malonate react selectively with aldehydes to afford alkenes within a few minutes, by adsorption on acidic clay (Montmorillonite K10) in a solvent-free reaction under microwave irradiation in a domestic oven.
ELECTROCHEMICAL CYCLIZATION OF TETRAMETHYL ESTERS OF 2-SUBSTITUTED PROPANE-1,1,3,3-TETRACARBOXYLIC ACIDS IN THE PRESENCE OF SALTS OF HYDROHALIC ACIDS
Elinson, M. N.,Fedukovich, S. K.,Nikishin, G. I.
, p. 2523 - 2529 (2007/10/02)
The chemical and electrochemical cyclization of tetramethyl esters of 2-substituted propane-1,1,3,3-tetracarboxylic acids in the presence of hydrohylic acid salt mediators were studied.It was found that the chemical variant of the cyclization of the corresponding α,α'-dianions of esters of propane-1,1,3,3-tetracarboxylic acids by the action of iodine or bromine is substantially inferior to the electrochemical variant.In the latter case, the esters of substituted cyclopropane-1,1,3,3-tetracarboxylic acids are formed in a 87-98percent yield.The tetramethyl ester of 2-isopropylpropane-1,1,3,3-tetracarboxylic acid, which under the electrolysis conditions decomposes according to a Michael retroreaction is an exception.
