56247-30-4

Upstream product

• 14811-73-5 10-oxo-decanoic acid methyl ester 
• 3761-92-0 n-hexylmagnesium bromide 
• 67-56-1 methanol 
• 57-10-3 1-hexadecylcarboxylic acid 
• 2640-94-0 methyl 10-hydroxydecanoate 
• 1679-53-4 10-hydroxydecanoic acid 
• 592-41-6 1-hexene 

Downstream Products

• 328935-20-2 methyl 10-(4-vinylphenoxy)hexadecanoate 

Relevant academic research and scientific papers

The CYPome of sorangium cellulosum so ce56 and identification of CYP109D1 as a new fatty acid hydroxylase

The first systematic study of the complete cytochrome P450 complement (CYPome) of Sorangium cellulosum So ce56, which is a producer of important secondary metabolites and has the largest bacterial genome sequenced to date, is presented. We describe the bioinformatic analysis of the So ce56 cytochrome P450 complement consisting of 21 putative P450 genes. Because fatty acids play a pivotal role during the complex life cycle of myxobacteria, we focused our studies on the characterization of fatty acid hydroxylases. Three novel potential fatty acid hydroxylases (CYP109D1, CYP264A1, and CYP266A1) were used for detailed characterization. One of them, CYP109D1 was able to perform subterminal hydroxylation of saturated fatty acids with the support of two autologous and one heterologous electron transfer system(s). The kinetic parameters for the product hydroxylation were derived.

A new family of polymerizable lyotropic liquid crystals: Control of feature size in cross-linked inverted hexagonal assemblies via monomer structure

An efficient and versatile synthesis of a series of polymerizable amphiphilic mesogens that affords control over tail length and position of the polymerizable group is described. The synthesis employs a novel and facile method of preparing styrene ethers. The monomers are sodium salts of styrene ether-modified fatty acids that can be used to form cross-linkable inverted hexagonal (HII) lyotropic liquid crystal (LLC) phases at ambient temperature with controllable nanometer-scale dimensions. Examination of a series of regioisomers with the same alkyl chain length but with the styrene ether group at different locations along the chain revealed that the position of the styrene ether has a profound effect on the dimensions of the resulting HII phase at a fixed temperature and composition. Increasing overall monomer tail length also has a significant, although smaller, effect on the unit cell dimensions of the LLC phase. By controlling the structure of the LLC monomer in this manner, cross-linked HII phases with interchannel distances (ICD) ranging from 29 to 54 A can be obtained. Furthermore, changing the counterion from Na+ to tetraalkylammonium ions leads to further expansion of the HII unit cell to a maximum ICD of 65 A, as well as to the production of a lamellar phase. Use of these monomers affords a new and unparalleled degree of control over phase structure and dimensions for the production of nanostructured organic materials.

AgAsF6 as safe alternative to AgClO4 for generating cationic zirconocene species: Utilities in Lewis acid-promoted selective C---C bond forming reactions

For generating cationic zirconocene species that are useful for organic synthesis, AgAsF6 proved to be an efficient catalyst that serves as a safe alternative to AgClO4. Scope and limitation is discussed on this new catalyst in the processes including (1) alkyl/alkenyl transfer reaction from organozirconocene chloride to aldehyde, (2) two- and four-carbon homologation of aldehyde, (3) dual synthetic methods of 1,3-dienes from aldehydes/ketones via 1,3-bimetallic species, and (4) three-component alkylative cycloaddition via o-quinodimethane species.

Grignard-type Addition of Alkenyl- and Alkylzirconocene Chloride to Aldehyde: Remarkable Catalytic Acceleration Effect of AgClO4

Nucleophilic addition of alkenylzirconocene chloride to aldehyde, which is ordinarily a slow reaction, is remarkably accelerated by a catalytic amount of AgClO4.The rate acceleration effect is also valid for the alkyl congener, Cp2Zr(Cl)R.