56352-94-4Relevant academic research and scientific papers
Anti-HIV, antimycobacterial and antimicrobial studies of newly synthesized 1,2,4-triazole clubbed benzothiazoles
Patel, Navin B.,Khan, Imran H.,Pannecouque, Christophe,De Clercq, Erik
, p. 1320 - 1329 (2013/04/10)
In an attempt to synthesize pharmacologically active molecules, we report here the synthesis and in vitro anti-HIV, antimycobacterial and antimicrobial activity of various series of 3-(3-pyridyl)-5-(4-substitutedphenyl)-4-(N- substituted-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole. The anti-HIV activity of the title compounds was evaluated as selective human immunodeficiency virus type-1 and -2 (HIV-1, HIV-2 RT) inhibitors, antitubercular activity against H37Rv using Lowenstein-Jensen agar method and antimicrobial activity against certain bacterial and fungal strains using the broth microdilution method. The synthesized compounds were characterized by FTIR, 1H-NMR,13C-NMR and mass spectral data together with elemental analysis.
HETEROCYCLIC COMPOUNDS AND THEIR METHODS OF USE
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Page/Page column 10-11, (2008/12/04)
The invention relates to heterocyclic derivatives, compositions comprising such compounds, and methods of preventing or treating conditions and disorders using such compounds and compositions. The heterocyclic derivatives, more particularly can be substit
Synthesis and characterization of new blue-greenish electroluminescent materials based on 1,3,4-oxadiazole-triazolopyridinone hybrids
Shin, Ming-Hsiang,Wong, Fung Fuh,Lin, Chun-Min,Chen, Wen-Yi,Yeh, Mou-Yung
, p. 212 - 219 (2008/02/07)
New functionalized oxadiazole-triazolopyridinone derivatives were synthesized via arcycloaddition. With the chromophores of triazolopyridinone, the photoluminescence spectra of these compounds in dichloromethane solution showed emission peaks between 430 and 520 nm. Following the spectroscopic studies, and the measurements of cyclic voltammogram, 1,3,4-oxadiazole- triazolopyridinone hybrids possess a great potential as highly efficient, blue-greenish, organic light-emitting devices materials.
